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Research Papers
Laboratoire de Génétique, Université Libre de Bruxelles, 1640 Rhode-St-Gen#x00E9;, Belgium
Abstract
The achaete-scute gene complex (AS-C) is a series of adjacent genes that play an essential role in the development of the Drosophila nervous system. A deletion of the entire complex results in the lack of all external sense organs and of most periphera1 neurons in the larva. The analysis of reciprocal left-right deletions reveals that the larval pattern of sense organs results from the addition of several independent subpatterns, each of which specifically requires a particular set of AS-C functions. Two of the subpatterns point to concealed homologies that are confirmed by the analysis of bxd mutants. We conclude that AS-C defines the basic topology of the pattern, rather than the type or precise location of the elements.
[Keywords: Sensory system; pattern formation; Drosophila larva; neurogenesis; achaete-scute complex]
Received December 23, 1986; revised version accepted February 2, 1987.
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