![[Feedback]](/icons/banner/feedbackACT.gif){kind=icon}
![[For Subscribers]](/icons/banner/subscriberACT.gif){kind=icon}
![[Archive]](/icons/banner/archiveACT.gif){kind=icon}
![[Search]](/icons/banner/searchACT.gif){kind=icon}
![[Contents]](/icons/banner/tocACT.gif){kind=icon}
|
|
|
|
|
||
Vol. 15, No. 15, pp. 1985-1997, August 1, 2001
1 Plant Biology Laboratory, Howard Hughes Medical
Institute, The Salk Institute for Biological Studies, La Jolla,
California 92037 USA; 2 Institute for Cellular and Molecular
Biology, The University of Texas at Austin, Austin, Texas 78712, USA;
3 Max-Delbrueck-Laboratorium in der Max-Planck-Gesellschaft,
D-50829 Koln, Germany; 4 School of Biological Sciences,
University of Auckland, Auckland, New Zealand
Polar auxin transport is crucial for the regulation of auxin action
and required for some light-regulated responses during plant
development. We have found that two mutants of
Arabidopsis
doc1, which displays altered expression of
light-regulated genes, and tir3, known for its reduced auxin
transporthave similar defects and define mutations in a single gene
that we have renamed BIG. BIG is very similar to the
Drosophila gene Calossin/Pushover, a member of a gene
family also present in Caenorhabditis elegans and human
genomes. The protein encoded by BIG is extraordinary in size,
560 kD, and contains several putative Zn-finger domains. Expression-profiling experiments indicate that altered expression of
multiple light-regulated genes in doc1 mutants can be
suppressed by elevated levels of auxin caused by overexpression of an
auxin biosynthetic gene, suggesting that normal auxin distribution is required to maintain low-level expression of these genes in the dark.
Double mutants of tir3 with the auxin mutants pin1,
pid, and axr1 display severe defects in auxin-dependent
growth of the inflorescence. Chemical inhibitors of auxin transport
change the intracellular localization of the auxin efflux carrier PIN1
in doc1/tir3 mutants, supporting the idea that BIG is required
for normal auxin efflux.
[Key Words: Auxin transport; light signaling; Arabidopsis]
CiteULike 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati What's this?
This article has been cited by other articles:
|
|
 |
|
  S. Barazesh and P. McSteen Barren inflorescence1 Functions in Organogenesis During Vegetative and Inflorescence Development in Maize Genetics, May 1, 2008; 179(1): 389 - 401. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Y. Shim, J. Wang, N. Asada, G. Neumayer, H. C. Tran, K.-i. Ishiguro, K. Sanada, Y. Nakatani, and M. D. Nguyen Protein 600 Is a Microtubule/Endoplasmic Reticulum-Associated Protein in CNS Neurons J. Neurosci., April 2, 2008; 28(14): 3604 - 3614. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. Lopez-Juez, E. Dillon, Z. Magyar, S. Khan, S. Hazeldine, S. M. de Jager, J. A.H. Murray, G. T.S. Beemster, L. Bogre, and H. Shanahan Distinct Light-Initiated Gene Expression and Cell Cycle Programs in the Shoot Apex and Cotyledons of Arabidopsis PLANT CELL, April 1, 2008; 20(4): 947 - 968. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Furutani, T. Kajiwara, T. Kato, B. S. Treml, C. Stockum, R. A. Torres-Ruiz, and M. Tasaka The gene MACCHI-BOU 4/ENHANCER OF PINOID encodes a NPH3-like protein and reveals similarities between organogenesis and phototropism at the molecular level Development, November 1, 2007; 134(21): 3849 - 3859. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 N. Yamaguchi, M. Suzuki, H. Fukaki, M. Morita-Terao, M. Tasaka, and Y. Komeda CRM1/BIG-Mediated Auxin Action Regulates Arabidopsis Inflorescence Development Plant Cell Physiol., September 1, 2007; 48(9): 1275 - 1290. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
X.-J. Yin, S. Volk, K. Ljung, N. Mehlmer, K. Dolezal, F. Ditengou, S. Hanano, S. J. Davis, E. Schmelzer, G. Sandberg, et al. Ubiquitin Lysine 63 Chain Forming Ligases Regulate Apical Dominance in Arabidopsis PLANT CELL, June 1, 2007; 19(6): 1898 - 1911. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Besseau, L. Hoffmann, P. Geoffroy, C. Lapierre, B. Pollet, and M. Legrand Flavonoid Accumulation in Arabidopsis Repressed in Lignin Synthesis Affects Auxin Transport and Plant Growth PLANT CELL, January 1, 2007; 19(1): 148 - 162. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M.-a. Ohto, S. Hayashi, S. Sawa, A. Hashimoto-Ohta, and K. Nakamura Involvement of HLS1 in Sugar and Auxin Signaling in Arabidopsis Leaves Plant Cell Physiol., December 1, 2006; 47(12): 1603 - 1611. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. E. Sieburth, G. K. Muday, E. J. King, G. Benton, S. Kim, K. E. Metcalf, L. Meyers, E. Seamen, and J. M. Van Norman SCARFACE Encodes an ARF-GAP That Is Required for Normal Auxin Efflux and Vein Patterning in Arabidopsis PLANT CELL, June 1, 2006; 18(6): 1396 - 1411. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. Paciorek and J. Friml Auxin signaling J. Cell Sci., April 1, 2006; 119(7): 1199 - 1202. [Full Text] [PDF]
|
|
|
|
|
|
Y. Dai, H. Wang, B. Li, J. Huang, X. Liu, Y. Zhou, Z. Mou, and J. Li Increased Expression of MAP KINASE KINASE7 Causes Deficiency in Polar Auxin Transport and Leads to Plant Architectural Abnormality in Arabidopsis PLANT CELL, February 1, 2006; 18(2): 308 - 320. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Yoshida, H. Kuriyama, and H. Fukuda Inhibition of Transdifferentiation into Tracheary Elements by Polar Auxin Transport Inhibitors Through Intracellular Auxin Depletion Plant Cell Physiol., December 1, 2005; 46(12): 2019 - 2028. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Poupart, A. M. Rashotte, G. K. Muday, and C. S. Waddell The rib1 Mutant of Arabidopsis Has Alterations in Indole-3-Butyric Acid Transport, Hypocotyl Elongation, and Root Architecture Plant Physiology, November 1, 2005; 139(3): 1460 - 1471. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Y. Nakatani, H. Konishi, A. Vassilev, H. Kurooka, K. Ishiguro, J.-i. Sawada, T. Ikura, S. J. Korsmeyer, J. Qin, and A. M. Herlitz From the Cover: p600, a unique protein required for membrane morphogenesis and cell survival PNAS, October 18, 2005; 102(42): 15093 - 15098. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. W. Whippo and R. P. Hangarter A Brassinosteroid-Hypersensitive Mutant of BAK1 Indicates That a Convergence of Photomorphogenic and Hormonal Signaling Modulates Phototropism Plant Physiology, September 1, 2005; 139(1): 448 - 457. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Woodward, S. M. Bemis, E. J. Hill, S. Sawa, T. Koshiba, and K. U. Torii Interaction of Auxin and ERECTA in Elaborating Arabidopsis Inflorescence Architecture Revealed by the Activation Tagging of a New Member of the YUCCA Family Putative Flavin Monooxygenases Plant Physiology, September 1, 2005; 139(1): 192 - 203. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. Tasaki, L. C. F. Mulder, A. Iwamatsu, M. J. Lee, I. V. Davydov, A. Varshavsky, M. Muesing, and Y. T. Kwon A Family of Mammalian E3 Ubiquitin Ligases That Contain the UBR Box Motif and Recognize N-Degrons Mol. Cell. Biol., August 15, 2005; 25(16): 7120 - 7136. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. DeMasi, K.-W. Huh, Y. Nakatani, K. Munger, and P. M. Howley Bovine papillomavirus E7 transformation function correlates with cellular p600 protein binding PNAS, August 9, 2005; 102(32): 11486 - 11491. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K.-W. Huh, J. DeMasi, H. Ogawa, Y. Nakatani, P. M. Howley, and K. Munger Association of the human papillomavirus type 16 E7 oncoprotein with the 600-kDa retinoblastoma protein-associated factor, p600 PNAS, August 9, 2005; 102(32): 11492 - 11497. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Lin and H. Wang Two Homologous ATP-Binding Cassette Transporter Proteins, AtMDR1 and AtPGP1, Regulate Arabidopsis Photomorphogenesis and Root Development by Mediating Polar Auxin Transport Plant Physiology, June 1, 2005; 138(2): 949 - 964. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. W. WOODWARD and B. BARTEL Auxin: Regulation, Action, and Interaction Ann. Bot., April 1, 2005; 95(5): 707 - 735. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Onodera, S.-G. Kong, M. Doi, K.-I. Shimazaki, J. Christie, N. Mochizuki, and A. Nagatani Phototropin from Chlamydomonas reinhardtii is Functional in Arabidopsis thaliana Plant Cell Physiol., February 1, 2005; 46(2): 367 - 374. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Lopez-Bucio, E. Hernandez-Abreu, L. Sanchez-Calderon, A. Perez-Torres, R. A. Rampey, B. Bartel, and L. Herrera-Estrella An Auxin Transport Independent Pathway Is Involved in Phosphate Stress-Induced Root Architectural Alterations in Arabidopsis. Identification of BIG as a Mediator of Auxin in Pericycle Cell Activation Plant Physiology, February 1, 2005; 137(2): 681 - 691. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Sun, S. Basu, S. R. Brady, R. L. Luciano, and G. K. Muday Interactions between Auxin Transport and the Actin Cytoskeleton in Developmental Polarity of Fucus distichus Embryos in Response to Light and Gravity Plant Physiology, May 1, 2004; 135(1): 266 - 278. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. Alabadi, J. Gil, M. A. Blazquez, and J. L. Garcia-Martinez Gibberellins Repress Photomorphogenesis in Darkness Plant Physiology, March 1, 2004; 134(3): 1050 - 1057. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. S.A. Al-Hammadi, Y. Sreelakshmi, S. Negi, I. Siddiqi, and R. Sharma The polycotyledon Mutant of Tomato Shows Enhanced Polar Auxin Transport Plant Physiology, September 1, 2003; 133(1): 113 - 125. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. J. Provart, P. Gil, W. Chen, B. Han, H.-S. Chang, X. Wang, and T. Zhu Gene Expression Phenotypes of Arabidopsis Associated with Sensitivity to Low Temperatures Plant Physiology, June 1, 2003; 132(2): 893 - 906. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Petrasek, A. Cerna, K. Schwarzerova, M. Elckner, D. A. Morris, and E. Zazimalova Do Phytotropins Inhibit Auxin Efflux by Impairing Vesicle Traffic? Plant Physiology, January 1, 2003; 131(1): 254 - 263. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. Scarpella, K. J.M. Boot, S. Rueb, and A. H. Meijer The Procambium Specification Gene Oshox1 Promotes Polar Auxin Transport Capacity and Reduces Its Sensitivity toward Inhibition Plant Physiology, November 1, 2002; 130(3): 1349 - 1360. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. Tobena-Santamaria, M. Bliek, K. Ljung, G. Sandberg, J. N.M. Mol, E. Souer, and R. Koes FLOOZY of petunia is a flavin mono-oxygenase-like protein required for the specification of leaf and flower architecture Genes & Dev., March 15, 2002; 16(6): 753 - 763. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. K. Muday and A. S. Murphy An Emerging Model of Auxin Transport Regulation PLANT CELL, February 1, 2002; 14(2): 293 - 299. [Full Text] [PDF]
|
|
|
|
|
|
Q. Tian, N. J. Uhlir, and J. W. Reed Arabidopsis SHY2/IAA3 Inhibits Auxin-Regulated Gene Expression PLANT CELL, February 1, 2002; 14(2): 301 - 319. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. J. Scanlon, D. C. Henderson, and B. Bernstein SEMAPHORE1 functions during the regulation of ancestrally duplicated knox genes and polar auxin transport in maize Development, January 6, 2002; 129(11): 2663 - 2673. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Yager, S. Richards, D. S. Hekmat-Scafe, D. D. Hurd, V. Sundaresan, D. R. Caprette, W. M. Saxton, J. R. Carlson, and M. Stern Control of Drosophila perineurial glial growth by interacting neurotransmitter-mediated signaling pathways PNAS, August 17, 2001; (2001) 191107698. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Yager, S. Richards, D. S. Hekmat-Scafe, D. D. Hurd, V. Sundaresan, D. R. Caprette, W. M. Saxton, J. R. Carlson, and M. Stern Control of Drosophila perineurial glial growth by interacting neurotransmitter-mediated signaling pathways PNAS, August 28, 2001; 98(18): 10445 - 10450. [Abstract] [Full Text] [PDF]
|
|
