QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Google Scholar Articles by Arvanitis, D. Articles by Davy, A. PubMed PubMed Citation Articles by Arvanitis, D. Articles by Davy, A. Related Content Signal Transduction Development Social Bookmarking                   What's this?

REVIEW

Eph/ephrin signaling: networks

Université de Toulouse, Centre de Biologie du Développement, 31062 Toulouse cedex 9, France; Centre National de la Recherche Scientifique (CNRS), UMR 5547, 31062 Toulouse, France

Bidirectional signaling has emerged as an important signature by which Ephs and ephrins control biological functions. Eph/ephrin signaling participates in a wide spectrum of developmental processes, and cross-regulation with other communication pathways lies at the heart of the complexity underlying their function in vivo. Here, we review in vitro and in vivo data describing molecular, functional, and genetic interactions between Eph/ephrin and other cell surface signaling pathways. The complexity of Eph/ephrin function is discussed in terms of the pathways that regulate Eph/ephrin signaling and also the pathways that are regulated by Eph/ephrin signaling.

[Keywords: Cell surface receptors; development; proteases; synaptic plasticity; cell adhesion]]

E-MAIL davy{at}cict.fr; FAX 33-5-61556507.

Article is online at http://www.genesdev.org/cgi/doi/10.1101/gad.1630408

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?