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Vol. 16, No. 24, pp. 3113-3129, December 15, 2002

REVIEW
Steroid signaling in plants and insectscommon themes, different pathways

Carl S. Thummel,¹ and Joanne Chory^2,3

¹ Howard Hughes Medical Institute, Department of Human Genetics, University of Utah, Salt Lake City, Utah 84112 USA; ² Howard Hughes Medical Institute, Plant Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, California 92037, USA

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	Introduction

Outside of mammals, two model systems have been the focus of intensive genetic studies aimed at defining the molecular mechanisms of steroid hormone actionthe flowering plant, Arabidopsis thaliana, and the fruit fly, Drosophila melanogaster. Studies in Arabidopsis have benefited from a detailed description of the brassinosteroid (BR) biosynthetic pathway, allowing the effects of mutations to be linked to specific enzymatic steps. More recently, the signaling cascade that functions downstream from BR production has been defined, revealing for the first time how the hormone can exert its effects on gene expression through a cell surface receptor and phosphorylation . . . [Full Text of this Article]

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