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PERSPECTIVE

Exploiting different ways to die

Howard Hughes Medical Institute and Center for Advanced Biotechnology and Medicine, Department of Molecular Biology and Biochemistry, Cancer Institute of New Jersey, Rutgers University, Piscataway, New Jersey 08854, USA

The first 100 words of the full text of this article appear below.

	Major modes of cell death

 
Far from a mere end point, cell death is an essential and highly orchestrated process. Developmental cell death is recognized to play a major role in morphogenesis and tissue sculpting, whereas cell death in mature organisms is essential for tissue homeostasis, wound healing, and elimination of infectious pathogens. Conversely, defective regulation or execution of cell death is also widely recognized as the basis for a spectrum of diseases, including many major human health foes such as diabetes, degenerative disorders, and cancer. Three major types of cell death have been distinguished, all of which contribute to proper development and well-being: apoptosis, . . . [Full Text of this Article]

	Subversion of cell death is cancer's deadly trick

 

	Turning the trick around: exploiting cell death in cancer control

 

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