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Perspective

The right place at the right time: regulation of daily timing by phosphorylation

¹ University of Groningen, Haren 9750 AA, The Netherlands; ² University of Padua, Padua 35131, Italy; ³ Ludwig-Maximilian University, Munich 80366, Germany

The first 100 words of the full text of this article appear below.

Each day we perform a ritual: We sleep for ~8 h, awaken and rise, and ~16 h later, we sleep again. This ritual is based on a temporal program that continues, although not necessarily exactly every 24 h, even if we are shielded from environmental signals such as light and dark, scheduled meals, or any social "rituals" such as work schedules. This endogenous, ~24-h oscillation, is called a circadian rhythm. Circadian clocks regulate processes from gene expression to behavior, and have been observed in all phyla. As such, the circadian system is a fundamental biological process—a part of life like . . . [Full Text of this Article]

	Circadian clocks in real life

 

	The importance of being phosphorylated (and dephosphorylated)

 

	Are there indications of a phoscillator in animals?

 

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