Genes and Development

Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
QUICK SEARCH:   [advanced]


     

GENES & DEVELOPMENT 21:1288-1291, 2007
©2007 by Cold Spring Harbor Laboratory Press; ISSN 0890-9369/ $5.00
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Hampsey, M.
Right arrow Articles by Kinzy, T. G.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Hampsey, M.
Right arrow Articles by Kinzy, T. G.
Related Content
Right arrow Chromatin and Gene Expression
Right arrow Post-transcriptional Control
Right arrowRelated Article
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?

PERSPECTIVE

Synchronicity: policing multiple aspects of gene expression by Ctk1

Michael Hampsey1 and Terri Goss Kinzy2,3

1 Department of Biochemistry, Division of Nucleic Acid Enzymology, University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School, Piscataway, New Jersey 08854, USA; 2 Department of Molecular Genetics, Microbiology and Immunology, University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School, Piscataway, New Jersey 08854, USA

The first 100 words of the full text of this article appear below.

Transcription and translation are coordinated events in all organisms. In prokaryotes, the process that couples these two events is clear: The ribosome begins translation of the nascent mRNA while the DNA template is still being transcribed. Indeed, cotranscriptional protein synthesis underlies key regulatory mechanisms in bacteria, including attenuation, the mechanism that regulates RNA polymerase processivity in response to ribosome movement along the mRNA. But how is transcription coordinated with translation in eukaryotic organisms, where mRNA is synthesized in the nucleus and protein synthesis occurs in the cytoplasm? Although these two events are spatially distinct, separated by the nuclear envelope, efficient . . . [Full Text of this Article]


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?

Related Article

The RNA polymerase II CTD kinase Ctk1 functions in translation elongation
Susanne Röther and Katja Sträßer
Genes & Dev. 2007 21: 1409-1421. [Abstract] [Full Text] [PDF]





Home Help [Feedback] [For Subscribers] [Archive] [Search] [Contents]
Genome Res. Learn. Mem.
Protein Science RNA Genes Dev.
Copyright © 2007 by Cold Spring Harbor Laboratory Press.