QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Niwa, H. Search for Related Content PubMed PubMed Citation Articles by Niwa, H. Related Content Chromatin and Gene Expression Development Related Article Social Bookmarking                   What's this?

PERSPECTIVE

Open conformation chromatin and pluripotency

Laboratory for Pluripotent Cell Studies, RIKEN Center for Developmental Biology (CDB), Kobe, Hyogo 650-0047, Japan

The first 100 words of the full text of this article appear below.

Pluripotency, the ability of a cell to give rise to all of the cells of an organism, is a fascinating and mysterious characteristic of embryonic stem (ES) cells. Recent extensive molecular studies of mouse ES cells have revealed the roles played by transcription factor networks and epigenetic processes in the maintenance of ES cell pluripotency (Niwa 2007). However, no direct evidence to connect these two mechanisms had been reported until in the previous issue of Genes & Development, in which Loh et al. (2007) presented new evidence concerning this missing link.

	Transcription factor network to maintain pluripotency

 
Analysis of transcription factors expressed in ES . . . [Full Text of this Article]

	Epigenetic mechanism to maintain pluripotency

 

	JmjC members cross genetic and epigenetic mechanisms to maintain pluripotency

 

	Is pluripotency the default state?

 

	Further genetics of the epigenetic mechanism in ES cells

 

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?

Related Article

Jmjd1a and Jmjd2c histone H3 Lys 9 demethylases regulate self-renewal in embryonic stem cells

Yuin-Han Loh, Weiwei Zhang, Xi Chen, Joshy George, and Huck-Hui Ng
Genes & Dev. 2007 21: 2545-2557. [Abstract] [Full Text] [PDF]

This article has been cited by other articles:

				M. Ekici, M. Hohl, F. Schuit, A. Martinez-Serrano, and G. Thiel Transcription of Genes Encoding Synaptic Vesicle Proteins in Human Neural Stem Cells: CHROMATIN ACCESSIBILITY, HISTONE METHYLATION PATTERN, AND THE ESSENTIAL ROLE OF REST J. Biol. Chem., April 4, 2008; 283(14): 9257 - 9268. [Abstract] [Full Text] [PDF]