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Vol. 14, No. 16, pp. 2085-2096, August 15, 2000
1 Departamento de Biología Molecular de Plantas,
Instituto de Biotecnología, Universidad Nacional Autónoma
de México, Cuernavaca, Morelos 62271, México;
2 Department of Genetics, Harvard Medical School, and
Department of Molecular Biology, Massachusetts General Hospital,
Boston, Massachusetts 02114 USA
Sugars have signaling roles in a wide variety of developmental
processes in plants. To elucidate the regulatory components that
constitute the glucose signaling network governing plant growth and
development, we have isolated and characterized two Arabidopsis
glucose insensitive mutants, gin5 and gin6, based on a
glucose-induced developmental arrest during early seedling morphogenesis. The T-DNA-tagged gin6 mutant abrogates the
glucose-induced expression of a putative transcription factor, ABI4,
previously shown to be involved in seed-specific abscisic acid (ABA)
responses. Thus, ABI4 might be a regulator involved in both glucose-
and seed-specific ABA signaling. The characterization of the
gin5 mutant, on the other hand, reveals that glucose-specific
accumulation of ABA is essential for hexokinase-mediated glucose
responses. Consistent with this result, we show that three
ABA-deficient mutants (aba1-1, aba2-1, and
aba3-2) are also glucose insensitive. Exogenous ABA can restore
normal glucose responses in gin5 and aba mutants but
not in gin6 plants. Surprisingly, only abi4 and abi5-1 but not other ABA-insensitive signaling mutants
(abi1-1, abi2-1, and abi3-1) exhibit glucose
insensitivity, indicating the involvement of a distinct ABA signaling
pathway in glucose responses. These results provide the first direct
evidence to support a novel and central role of ABA in plant glucose
responses mediated through glucose regulation of both ABA levels by
GIN5 and ABA signaling by GIN6/ABI4.
[Key Words: Glucose insensitive; Arabidopsis thaliana; glucose regulation; ABA; abi; hexokinase]
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|
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|
|
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|
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|
|
|
|
 |
|
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|
|
|
|
 |
|
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|
|
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|
|
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|
|
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|
|
|
|
|
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|
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|
|
|
|
|
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|
|
|
|
|
N. A. Eckardt, H.-T. Cho, R. M. Perrin, and M. R. Willmann Plant Biology 2001 PLANT CELL, October 1, 2001; 13(10): 2165 - 2173. [Full Text] [PDF]
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