Genes & Development -- Table of Contents (September 1 1998, 12 [17])

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Volume 12, Issue 17: September 1, 1998 [Index by Author] [Cover Caption]

Other Issues:

Perspectives

Research Communications

Research Papers

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Perspectives:

Terence H. Rabbitts: LMO T-cell translocation oncogenes typify genes activated by chromosomal translocations that alter transcription and developmental processes
Genes Dev. 1998 12: 2651-2657. [Full Text] [PDF]

Research Communications:

Serge Y. Fuchs, Victor Adler, Thomas Buschmann, Zhimin Yin, Xiangwei Wu, Stephen N. Jones, and Zeev Ronai: JNK targets p53 ubiquitination and degradation in nonstressed cells
Genes Dev. 1998 12: 2658-2663. [Abstract] [Full Text] [PDF]

Research Papers:

R. William Henry, Vivek Mittal, Beicong Ma, Ryuji Kobayashi, and Nouria Hernandez: SNAP19 mediates the assembly of a functional core promoter complex (SNAP_c) shared by RNA polymerases II and III
Genes Dev. 1998 12: 2664-2672. [Abstract] [Full Text] [PDF]

Arie Kaffman, Nicole Miller Rank, and Erin K. O'Shea: Phosphorylation regulates association of the transcription factor Pho4 with its import receptor Pse1/Kap121
Genes Dev. 1998 12: 2673-2683. [Abstract] [Full Text] [PDF]

Peter M. Pryciak and Frederick A. Huntress: Membrane recruitment of the kinase cascade scaffold protein Ste5 by the G $beta$ $gamma$ complex underlies activation of the yeast pheromone response pathway
Genes Dev. 1998 12: 2684-2697. [Abstract] [Full Text] [PDF]

David Stuart and Curt Wittenberg: CLB5 and CLB6 are required for premeiotic DNA replication and activation of the meiotic S/M checkpoint
Genes Dev. 1998 12: 2698-2710. [Abstract] [Full Text] [PDF]

Amin Ghabrial, Robert P. Ray, and Trudi Schüpbach: okra and spindle-B encode components of the RAD52 DNA repair pathway and affect meiosis and patterning in Drosophila oogenesis
Genes Dev. 1998 12: 2711-2723. [Abstract] [Full Text] [PDF]

Hideki Nakagoshi, Minako Hoshi, Yo-ichi Nabeshima, and Fumio Matsuzaki: A novel homeobox gene mediates the Dpp signal to establish functional specificity within target cells
Genes Dev. 1998 12: 2724-2734. [Abstract] [Full Text] [PDF]

Heiko Peters, Annette Neubüser, Klaus Kratochwil, and Rudi Balling: Pax9-deficient mice lack pharyngeal pouch derivatives and teeth and exhibit craniofacial and limb abnormalities
Genes Dev. 1998 12: 2735-2747. [Abstract] [Full Text] [PDF]

Sarah Newlands, Linda K. Levitt, C. Stephen Robinson, A.B. Carmen Karpf, Vanessa R.M. Hodgson, Robert P. Wade, and Edna C. Hardeman: Transcription occurs in pulses in muscle fibers
Genes Dev. 1998 12: 2748-2758. [Abstract] [Full Text] [PDF]

Göran Baurén, Sergey Belikov, and Lars Wieslander: Transcriptional termination in the Balbiani ring 1 gene is closely coupled to 3'-end formation and excision of the 3'-terminal intron
Genes Dev. 1998 12: 2759-2769. [Abstract] [Full Text] [PDF]

Nathalie F. Vanzo, Yeun Shan Li, Béatrice Py, Erwin Blum, Christopher F. Higgins, Lelia C. Raynal, Henry M. Krisch, and Agamemnon J. Carpousis: Ribonuclease E organizes the protein interactions in the Escherichia coli RNA degradosome
Genes Dev. 1998 12: 2770-2781. [Abstract] [Full Text] [PDF]

Xing Dai and Lucia B. Rothman-Denes: Sequence and DNA structural determinants of N4 virion RNA polymerase-promoter recognition
Genes Dev. 1998 12: 2782-2790. [Abstract] [Full Text] [PDF]

Frederick W. Whipple, Emmeline F. Hou, and Ann Hochschild: Amino acid-amino acid contacts at the cooperativity interface of the bacteriophage $lambda$ and P22 repressors
Genes Dev. 1998 12: 2791-2802. [Abstract] [Full Text] [PDF]

Stacy K. Merickel, Michael J. Haykinson, and Reid C. Johnson: Communication between Hin recombinase and Fis regulatory subunits during coordinate activation of Hin-catalyzed site-specific DNA inversion
Genes Dev. 1998 12: 2803-2816. [Abstract] [Full Text] [PDF]

Cover Caption:

Cover

Model of the Hin invertasome that assembles during site-specific DNA inversion. Hin recombinase dimers bind to each of thetwo recombination sites hixL and hixR, and Fis dimers bind totwo sites within the recombinational enhancer segment. The threesegments assemble into an invertasome structure at the base ofa DNA branch on supercoiled DNA. Within this structure, Fis activatesthe catalytic properties of Hin to initiate recombination. (Topleft) Schematic representation of the invertasome assembled ona plasmid substrate; (top right) molecular model of Fis boundto the two enhancer domains. The side chains of the three aminoacids within the mobile Fis $beta$ -hairpin arms (highlighted in pink)that are critical for activating Hin are shown. Only one of the $beta$ -hairpin arms is required to activate Hin. (Bottom) Molecularmodel of the invertasome. The enhancer segment has been rotatedapproximately 90° about the z axis in comparison to the top right.(For details, see Merickel et al., p. 2803.)