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Caulobacter crescentus and the cell division initiation protein FtsZ through the cell cycle. Shown are electron micrographs of Caulobacter (top) and immunofluorescence analysis of FtsZ (bottom) at different stages through the cell cycle. The cell cycle initiates with a swarmer cell (left) that contains a single polar flagellum (wavy line), which differentiates into a stalked cell (third from left) by shedding the flagellum and synthesizing a stalk at the same pole. The predivisional cell (fourth from left) contains a single flagellum synthesized at the pole opposite the stalk. Cell division produces a swarmer cell and stalk cell (right). The replication-competent stalk cell contains FtsZ, whereas the replication-incompetent swarmer cell lacks FtsZ. (For details, see Kelly et al., p. 880.)