QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

LIM-4 controls dye-filling properties of olfactory neurons. Shown here are confocal sections of worms expressing GFP (green) in AWB and AWC neurons, soaked in lipophilic dye DiD (shown as red). The merge is shown as yellow. The more dorsal GFP-expressing cell is AWB; the more ventral cell is AWC. In wild-type animals (top), AWB but not AWC takes up dye; in lim-4 animals (bottom), neither AWB nor AWC neurons take up dye. Ectopic expression of LIM-4 in transgenic worms (right) results in dye uptake in both AWB and AWC neurons, demonstrating that LIM-4 can repress AWC fate and promote AWB fate in the AWC neuron. (For details, see Sagasti et al., p. 1794.)