Genes & Development -- Table of Contents (November 1 1999, 13 [21])

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Volume 13, Issue 21: November 1, 1999 [Index by Author] [Cover Caption]

Other Issues:

Perspectives

Reviews

Research Papers

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Perspectives:

Jeffrey T. Winston, Claire Chu, and J. Wade Harper: Culprits in the degradation of cyclin E apprehended
Genes Dev. 1999 13: 2751-2757. [Full Text] [PDF]

Reviews:

Dennis S. Rice and Tom Curran: Mutant mice with scrambled brains: understanding the signaling pathways that control cell positioning in the CNS
Genes Dev. 1999 13: 2758-2773. [Full Text] [PDF]

Research Papers:

Angela R. Winnier, James Y.-J. Meir, Jennifer M. Ross, Nektarios Tavernarakis, Monica Driscoll, Takeshi Ishihara, Isao Katsura, and David M. Miller, III: UNC-4/UNC-37-dependent repression of motor neuron-specific genes controls synaptic choice in Caenorhabditis elegans
Genes Dev. 1999 13: 2774-2786. [Abstract] [Full Text] [PDF]

Dario Acampora, Maria Pia Postiglione, Virginia Avantaggiato, Maria Di Bonito, Flora M. Vaccarino, Jacques Michaud, and Antonio Simeone: Progressive impairment of developing neuroendocrine cell lineages in the hypothalamus of mice lacking the Orthopedia gene
Genes Dev. 1999 13: 2787-2800. [Abstract] [Full Text] [PDF]

Dorit B. Donoviel, Anna-Katerina Hadjantonakis, Masaki Ikeda, Hui Zheng, Peter St George Hyslop, and Alan Bernstein: Mice lacking both presenilin genes exhibitearlyembryonic patterningdefects
Genes Dev. 1999 13: 2801-2810. [Abstract] [Full Text] [PDF]

Xiao-Li Zhan and Kun-Liang Guan: A specific protein-protein interaction accounts for the in vivo substrate selectivity of Ptp3 towards the Fus3 MAP kinase
Genes Dev. 1999 13: 2811-2827. [Abstract] [Full Text] [PDF]

Gelin Wang, Bing Wang, and Jin Jiang: Protein kinase A antagonizes Hedgehog signaling by regulating both the activator and repressor forms of Cubitus interruptus
Genes Dev. 1999 13: 2828-2837. [Abstract] [Full Text] [PDF]

Chad A. Rappleye, Alexander R. Paredez, Carol W. Smith, Kent L. McDonald, and Raffi V. Aroian: The coronin-like protein POD-1 is required for anterior-posterior axis formation and cellular architecture in the nematode Caenorhabditis elegans
Genes Dev. 1999 13: 2838-2851. [Abstract] [Full Text] [PDF]

Mikhail A. Nikiforov, James F. Smothers, Martin A. Gorovsky, and C. David Allis: Excision of micronuclear-specific DNA requires parental expression of Pdd2p andoccursindependentlyfromDNA replication in Tetrahymena thermophila
Genes Dev. 1999 13: 2852-2862. [Abstract] [Full Text] [PDF]

Katherine L. Friedman and Thomas R. Cech: Essential functions of amino-terminal domains in the yeast telomerase catalytic subunit revealed by selection for viable mutants
Genes Dev. 1999 13: 2863-2874. [Abstract] [Full Text] [PDF]

Richard McCulloch and J. David Barry: A role for RAD51 and homologous recombination in Trypanosoma brucei antigenic variation
Genes Dev. 1999 13: 2875-2888. [Abstract] [Full Text] [PDF]

Mohammad R. Motamedi, Susan K. Szigety, and Susan M. Rosenberg: Double-strand-break repair recombination in Escherichia coli: physical evidence for a DNA replication mechanism in vivo
Genes Dev. 1999 13: 2889-2903. [Abstract] [Full Text] [PDF]

Cover Caption:

Cover

C. elegans POD-1 is required for polarity and cell structure in the early embryo. Shown here is an immunofluorescence analysisof a wild-type one-cell embryo stained with POD-1 antibodies (green)and DAPI to visualize the DNA (blue). POD-1 localizes asymmetricallyto the anterior (left). In pod-1 embryos, POD-1 staining is absentand anterior-posterior polarity is lost (not shown). (For details,see Rappleye et al., p. 2838.)