Genes & Development -- Table of Contents (December 15 1999, 13 [24])

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Volume 13, Issue 24: December 15, 1999 [Index by Author] [Cover Caption]

Other Issues:

Perspectives

Research Communications

Research Papers

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Perspectives:

Frédéric Relaix and Margaret Buckingham: From insect eye to vertebrate muscle: redeployment of a regulatory network
Genes Dev. 1999 13: 3171-3178. [Full Text] [PDF]

Research Communications:

Joe Rodriguez and Yuri Lazebnik: Caspase-9 and APAF-1 form an active holoenzyme
Genes Dev. 1999 13: 3179-3184. [Abstract] [Full Text] [PDF]

Terry P. Yamaguchi, Shinji Takada, Yoshiaki Yoshikawa, Nongying Wu, and Andrew P. McMahon: T (Brachyury) is a direct target of Wnt3a during paraxial mesoderm specification
Genes Dev. 1999 13: 3185-3190. [Abstract] [Full Text] [PDF]

Research Papers:

Thomas Tuschl, Phillip D. Zamore, Ruth Lehmann, David P. Bartel, and Phillip A. Sharp: Targeted mRNA degradation by double-stranded RNA in vitro
Genes Dev. 1999 13: 3191-3197. [Abstract] [Full Text] [PDF]

Valentina Perissi, Lena M. Staszewski, Eileen M. McInerney, Riki Kurokawa, Anna Krones, David W. Rose, Mill H. Lambert, Michael V. Milburn, Christopher K. Glass, and Michael G. Rosenfeld: Molecular determinants of nuclear receptor-corepressor interaction
Genes Dev. 1999 13: 3198-3208. [Abstract] [Full Text] [PDF]

Laszlo Nagy, Hung-Ying Kao, James D. Love, Chuan Li, Ester Banayo, John T. Gooch, V. Krishna, K. Chatterjee, Ronald M. Evans, and John W.R. Schwabe: Mechanism of corepressor binding and release from nuclear hormone receptors
Genes Dev. 1999 13: 3209-3216. [Abstract] [Full Text] [PDF]

Georgia A. Patikoglou, Joseph L. Kim, Liping Sun, Sang-Hwa Yang, Thomas Kodadek, and Stephen K. Burley: TATA element recognition by the TATA box-binding protein has been conserved throughout evolution
Genes Dev. 1999 13: 3217-3230. [Abstract] [Full Text] [PDF]

Tiffany A. Heanue, Ram Reshef, Richard J. Davis, Graeme Mardon, Guillermo Oliver, Stanislav Tomarev, Andrew B. Lassar, and Clifford J. Tabin: Synergistic regulation of vertebrate muscle development by Dach2, Eya2, and Six1, homologs of genes required for Drosophila eye formation
Genes Dev. 1999 13: 3231-3243. [Abstract] [Full Text] [PDF]

Deborah C.I. Goberdhan, Nuria Paricio, Emma C. Goodman, Marek Mlodzik, and Clive Wilson: Drosophila tumor suppressor PTEN controls cell size and number by antagonizing the Chico/PI3-kinase signaling pathway
Genes Dev. 1999 13: 3244-3258. [Abstract] [Full Text] [PDF]

Karin Schumacher, Dionne Vafeados, Melissa McCarthy, Heven Sze, Thea Wilkins, and Joanne Chory: The Arabidopsis det3 mutant reveals a central role for the vacuolar H⁺-ATPase in plant growth and development
Genes Dev. 1999 13: 3259-3270. [Abstract] [Full Text] [PDF]

Maria E. Cardenas, N. Shane Cutler, Michael C. Lorenz, Charles J. Di Como, and Joseph Heitman: The TOR signaling cascade regulates gene expression in response to nutrients
Genes Dev. 1999 13: 3271-3279. [Abstract] [Full Text] [PDF]

Farhat Osman, Nayef Jarrous, Yitzhak Ben-Asouli, and Raymond Kaempfer: A cis-acting element in the 3'-untranslated region of human TNF- $alpha$ mRNA renders splicing dependent on the activation of protein kinase PKR
Genes Dev. 1999 13: 3280-3293. [Abstract] [Full Text] [PDF]

Cover Caption:

Cover

Dach2, a vertebrate homolog of Drosophila dachshund, is expressed in the muscle precursor population of the developing somiteand in muscle precursors that migrate into the body wall and limbbuds. Shown here is a stage 17 chick embryo stained for Dach2RNA expression (purple) by whole-mount in situ hybridization.Expression is seen in the muscle precursors and in the dorsalneural tube. Dach2 synergizes with Eya2 and Six1 to regulate muscledevelopment. (For details, see Heanue et al., p. 3231; see alsothe related Perspective by Relaix and Buckingham, p. 3171.)