|
|
|
![]() Other Issues: |
|
||||||
The E2F and DP families of heterodimeric transcription factors have a central role in the control of gene expression in a cell cycle-dependent manner. The structure of the DNA-binding domains of E2F4 (red) and DP2 (blue) bound to DNA (gray) shows that the E2F and DP proteins use the same fold and conserved residues to recognize DNA. (For details, see Zheng et al., p. 666.)