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Mcl-1 expression in preimplantation mouse embryos. Shown here is an in situ analysis of a blastocyst-stage, wild-type embryo stained with the Mcl-1 antisense probe. Mcl-1, a Bcl-2 family member, is expressed both in the trophectoderm and in the inner cell mass. (For details, see Rinkenberger et al., p. 23).