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Volume 14, Issue 14:  July 15, 2000  [Index by Author]  [Cover Caption] 

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  Reviews
  Research Communications
  Research Papers
  Errata
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To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

Reviews:

Laurie H. Glimcher and Kenneth M. Murphy
Lineage commitment in the immune system: the T helper lymphocyte grows up
Genes Dev. 2000 14: 1693-1711. [Full Text] [PDF]  

Colin R. Goding
Mitf from neural crest to melanoma: signal transduction and transcription in the melanocyte lineage
Genes Dev. 2000 14: 1712-1728. [Full Text] [PDF]  

Research Communications:

Qiutang Li, Gabriela Estepa, Sylvie Memet, Alain Israel, and Inder M. Verma
Complete lack of NF-kappa B activity in IKK1 and IKK2 double-deficient mice: additional defect in neurulation
Genes Dev. 2000 14: 1729-1733. [Abstract] [Full Text] [PDF]  

Research Papers:

Atsushi Suzuki, Hirofumi Doi, Fumiko Matsuzawa, Sei-ichi Aikawa, Kyoko Takiguchi, Hirokazu Kawano, Midori Hayashida, and Susumu Ohno
Bcl-2 antiapoptotic protein mediates verotoxin II-induced cell death: possible association between Bcl-2 and tissue failure by E. coli O157:H7
Genes Dev. 2000 14: 1734-1740. [Abstract] [Full Text] [PDF]  

Ken-ichi Tago, Tsutomu Nakamura, Michiru Nishita, Junko Hyodo, Shin-ichi Nagai, Yoji Murata, Shungo Adachi, Susumu Ohwada, Yasuo Morishita, Hiroshi Shibuya, and Tetsu Akiyama
Inhibition of Wnt signaling by ICAT, a novel beta -catenin-interacting protein
Genes Dev. 2000 14: 1741-1749. [Abstract] [Full Text] [PDF]  

Lingyang Zhu, Jill Wilken, Nelson B. Phillips, Umadevi Narendra, Ging Chan, Stephen M. Stratton, Stephen B. Kent, and Michael A. Weiss
Sexual dimorphism in diverse metazoans is regulated by a novel class of intertwined zinc fingers
Genes Dev. 2000 14: 1750-1764. [Abstract] [Full Text] [PDF]  

Allyson J. Whittaker, Irena Royzman, and Terry L. Orr-Weaver
Drosophila Double parked: a conserved, essential replication protein that colocalizes with the origin recognition complex and links DNA replication with mitosis and the down-regulation of S phase transcripts
Genes Dev. 2000 14: 1765-1776. [Abstract] [Full Text] [PDF]  

Haiyan Qi and Virginia A. Zakian
The Saccharomyces telomere-binding protein Cdc13p interacts with both the catalytic subunit of DNA polymerase alpha  and the telomerase-associated Est1 protein
Genes Dev. 2000 14: 1777-1788. [Abstract] [Full Text] [PDF]  

Zhongjun Qin and Stanley N. Cohen
Long palindromes formed in Streptomyces by nonrecombinational intra-strand annealing
Genes Dev. 2000 14: 1789-1796. [Abstract] [Full Text] [PDF]  

Kazushi Inoue, Renren Wen, Jerold E. Rehg, Masashi Adachi, John L. Cleveland, Martine F. Roussel, and Charles J. Sherr
Disruption of the ARF transcriptional activator DMP1 facilitates cell immortalization, Ras transformation, and tumorigenesis
Genes Dev. 2000 14: 1797-1809. [Abstract] [Full Text] [PDF]  

Khanh D. Huynh, Wolfgang Fischle, Eric Verdin, and Vivian J. Bardwell
BCoR, a novel corepressor involved in BCL-6 repression
Genes Dev. 2000 14: 1810-1823. [Abstract] [Full Text] [PDF]  

P.R. Kramer and Susan Wray
Novel gene expressed in nasal region influences outgrowth of olfactory axons and migration of luteinizing hormone-releasing hormone (LHRH) neurons
Genes Dev. 2000 14: 1824-1834. [Abstract] [Full Text] [PDF]  

Errata:


Genes Dev. 2000 14: 1835. [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.


Cover Caption:

Cover

Solution structure of the Drosophila Doublesex (DSX) DM domain. Shown here is a stereo image of the DM domain as outlined in schematic form. The main chain structures are aligned according to the main chain atoms of residues 41-81. The sites nucleate a unified globular domain containing two alpha -helices. The position of the two bound Zn2+ atoms are shown as red spheres. This novel intertwined zinc finger module targets the minor groove of B-form DNA and binds without bending the DNA. (For details, see Zhu et al., p. 1750.)



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