Genes & Development -- Table of Contents (August 1 2000, 14 [15])

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Volume 14, Issue 15: August 1, 2000 [Index by Author] [Cover Caption]

Other Issues:

Reviews

Research Communications

Research Papers

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Reviews:

Paul Polakis: Wnt signaling and cancer
Genes Dev. 2000 14: 1837-1851. [Full Text] [PDF]

Bassem A. Hassan and Hugo J. Bellen: Doing the MATH: is the mouse a good model for fly development?
Genes Dev. 2000 14: 1852-1865. [Full Text] [PDF]

Research Communications:

Seung K. Kim, Matthias Hebrok, En Li, S. Paul Oh, Heinrich Schrewe, Erin B. Harmon, Joon S. Lee, and Douglas A. Melton: Activin receptor patterning of foregut organogenesis
Genes Dev. 2000 14: 1866-1871. [Abstract] [Full Text] [PDF]

Research Papers:

Kaveh Ashrafi, Stephen S. Lin, Jill K. Manchester, and Jeffrey I. Gordon: Sip2p and its partner Snf1p kinase affect aging in S. cerevisiae
Genes Dev. 2000 14: 1872-1885. [Abstract] [Full Text] [PDF]

Robert S. Weiss, Tamar Enoch, and Philip Leder: Inactivation of mouse Hus1 results in genomic instability and impaired responses to genotoxic stress
Genes Dev. 2000 14: 1886-1898. [Abstract] [Full Text] [PDF]

Takashi Ito, Tsuyoshi Ikehara, Takeya Nakagawa, W. Lee Kraus, and Masami Muramatsu: p300-Mediated acetylation facilitates the transfer of histone H2A-H2B dimers from nucleosomes to a histone chaperone
Genes Dev. 2000 14: 1899-1907. [Abstract] [Full Text] [PDF]

Christopher R. Kaffer, Madhulika Srivastava, Kye-Yoon Park, Elizabeth Ives, Sandra Hsieh, Juan Batlle, Alexander Grinberg, Sing-Ping Huang, and Karl Pfeifer: A transcriptional insulator at the imprinted H19/Igf2 locus
Genes Dev. 2000 14: 1908-1919. [Abstract] [Full Text] [PDF]

Cor F. Calkhoven, Christine Müller, and Achim Leutz: Translational control of C/EBP $alpha$ and C/EBP $beta$ isoform expression
Genes Dev. 2000 14: 1920-1932. [Abstract] [Full Text] [PDF]

Patricia E. Kuwabara, Min-Ho Lee, Tim Schedl, and Gregory S.X.E. Jefferis: A C. elegans patched gene, ptc-1, functions in germ-line cytokinesis
Genes Dev. 2000 14: 1933-1944. [Abstract] [Full Text] [PDF]

Anne E. Uv, Peggy Roth, Nikos Xylourgidis, Anna Wickberg, Rafael Cantera, and Christos Samakovlis: members only encodes a Drosophila nucleoporin required for Rel protein import and immune response activation
Genes Dev. 2000 14: 1945-1957. [Abstract] [Full Text] [PDF]

Hsu-Liang Hsieh, Haruko Okamoto, Mingli Wang, Lay-Hong Ang, Minami Matsui, Horward Goodman, and Xing Wang Deng: FIN219, an auxin-regulated gene, defines a link between phytochrome A and the downstream regulator COP1 in light control of Arabidopsis development
Genes Dev. 2000 14: 1958-1970. [Abstract] [Full Text] [PDF]

Joep P.P. Muyrers, Youming Zhang, Fraenk Buchholz, and A. Francis Stewart: RecE/RecT and Red $alpha$ /Red $beta$ initiate double-stranded break repair by specifically interacting with their respective partners
Genes Dev. 2000 14: 1971-1982. [Abstract] [Full Text] [PDF]

Cover Caption:

Cover

Premature aging of yeast cells that lack protein N-myristoylation. Shown here is a multilabel immunofluorescence analysisof yeast cells with a temperature-sensitive NMT1 allele. Cellsare stained with DAPI to visualize nuclear DNA (purple); nucleoliare visualized as red (right), and Sir3p is visualized as green(bottom). Colocalization of Sir3p with nucleolar fragments appearsyellow in the merged image (top). The background shows an enlargedimage of an NMT1 cell with the nucleolus intact. NMT1 encodesMyristoylCoA:protein N-myristoyltransferase, which covalentlylinks myristate to proteins. nmt1-451D encodes an enzyme witha reduced affinity for myristoylCoA and nmt1-451D cells exhibitdecreased resistance to nutrient deprivation. Deletion of theN-myristoylprotein Sip2p accelerates aging by increasing the activityof Snf1p, a serine/threonine kinase involved in regulating cellularresponses to glucose starvation. (For details, see Ashrafi etal., p. 1872.)