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A role for abscisic acid (ABA) in glucose regulation in Arabidopsis. Shown here is a glucose insensitive (gin) mutant, gin5, seedling grown in the presence of 7% glucose. In comparison to wild-type seedlings (not shown) gin5 mutants develop green and expanded cotyledons when grown in the presence of glucose. Analysis of gin5 demonstrates that glucose-specific accumulation of ABA is essential for hexokinase-mediated glucose responses. (For details, see Arenas-Huertero et al., p. 2085).