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Volume 14, Issue 17:  September 1, 2000  [Index by Author]  [Cover Caption] 

Cover Image
Other Issues:
  Reviews
  Research Communications
  Research Papers
   
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Reviews:

Thiennu H. Vu and Zena Werb
Matrix metalloproteinases: effectors of development and normal physiology
Genes Dev. 2000 14: 2123-2133. [Full Text] [PDF]  

Research Communications:

Maike Sander, Sussan Paydar, Johan Ericson, James Briscoe, Elizabeth Berber, Michael German, Thomas M. Jessell, and John L.R. Rubenstein
Ventral neural patterning by Nkx homeobox genes: Nkx6.1 controls somatic motor neuron and ventral interneuron fates
Genes Dev. 2000 14: 2134-2139. [Abstract] [Full Text] [PDF]  

Christian Wolf and Reinhard Schuh
Single mesodermal cells guide outgrowth of ectodermal tubular structures in Drosophila
Genes Dev. 2000 14: 2140-2145. [Abstract] [Full Text] [PDF]  

Research Papers:

Bradley S. Cobb, Susana Morales-Alcelay, Gary Kleiger, Karen E. Brown, Amanda G. Fisher, and Stephen T. Smale
Targeting of Ikaros to pericentromeric heterochromatin by direct DNA binding
Genes Dev. 2000 14: 2146-2160. [Abstract] [Full Text] [PDF]  

Hong Zhang and Scott W. Emmons
A C. elegans mediator protein confers regulatory selectivity on lineage-specific expression of a transcription factor gene
Genes Dev. 2000 14: 2161-2172. [Abstract] [Full Text] [PDF]  

Quinn M. Mitrovich and Philip Anderson
Unproductively spliced ribosomal protein mRNAs are natural targets of mRNA surveillance in C. elegans
Genes Dev. 2000 14: 2173-2184. [Abstract] [Full Text] [PDF]  

Rónán C. O'Hagan, Michael Ohh, Gregory David, Ignacio Moreno de Alboran, Frederick W. Alt, William G. Kaelin, Jr., and Ronald A. DePinho
Myc-enhanced expression of Cul1 promotes ubiquitin-dependent proteolysis and cell cycle progression
Genes Dev. 2000 14: 2185-2191. [Abstract] [Full Text] [PDF]  

Oliver Leismann, Alf Herzig, Stefan Heidmann, and Christian F. Lehner
Degradation of Drosophila PIM regulates sister chromatid separation during mitosis
Genes Dev. 2000 14: 2192-2205. [Abstract] [Full Text] [PDF]  

Galina Petukhova, Patrick Sung, and Hannah Klein
Promotion of Rad51-dependent D-loop formation by yeast recombination factor Rdh54/Tid1
Genes Dev. 2000 14: 2206-2215. [Abstract] [Full Text] [PDF]  

Rupal S. Bhatt, Toshifumi Tomoda, Yin Fang, and Mary E. Hatten
Discoidin domain receptor 1 functions in axon extension of cerebellar granule neurons
Genes Dev. 2000 14: 2216-2228. [Abstract] [Full Text] [PDF]  

Robert T. Gampe, Jr., Valerie G. Montana, Millard H. Lambert, G. Bruce Wisely, Michael V. Milburn, and H. Eric Xu
Structural basis for autorepression of retinoid X receptor by tetramer formation and the AF-2 helix
Genes Dev. 2000 14: 2229-2241. [Abstract] [Full Text] [PDF]  

Yuli Guo, Chih Min Lew, and Jay D. Gralla
Promoter opening by sigma 54 and sigma 70 RNA polymerases: sigma factor-directed alterations in the mechanism and tightness of control
Genes Dev. 2000 14: 2242-2255. [Abstract] [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.


Cover Caption:

Cover

Structure of the retinoid X receptor (RXR) tetramer/trans-RA (tRA) complex. Shown here is an overview of the RXR tetramer structure. Each protein monomer is independently colored. The two tRA-isomers are shown in space-filling representation, with green indicating carbons and red indicating oxygens. The tRA binds to RXR as a nonactivating ligand and results in an inactivated tetrameric complex. (For details, see Gampe, Jr., et al., p. 2229.)



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