Genes & Development -- Table of Contents (September 15 2000, 14 [18])

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Volume 14, Issue 18: September 15, 2000 [Index by Author] [Cover Caption]

Other Issues:

Perspectives

Research Communications

Research Papers

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Perspectives:

Andrew P. McMahon: Neural patterning: The role of Nkx genes in the ventral spinal cord
Genes Dev. 2000 14: 2261-2264. [Full Text] [PDF]

Mark E. Ewen: Where the cell cycle and histones meet
Genes Dev. 2000 14: 2265-2270. [Full Text] [PDF]

Research Communications:

Shu-Huei Wang, Amanda Simcox, and Gerard Campbell: Dual role for Drosophila epidermal growth factor receptor signaling in early wing disc development
Genes Dev. 2000 14: 2271-2276. [Abstract] [Full Text] [PDF]

Paul Kalitsis, Elizabeth Earle, Kerry J. Fowler, and K.H. Andy Choo: Bub3 gene disruption in mice reveals essential mitotic spindle checkpoint function during early embryogenesis
Genes Dev. 2000 14: 2277-2282. [Abstract] [Full Text] [PDF]

Research Papers:

Jiyong Zhao, Brian K. Kennedy, Brandon D. Lawrence, David A. Barbie, A. Gregory Matera, Jonathan A. Fletcher, and Ed Harlow: NPAT links cyclin E-Cdk2 to the regulation of replication-dependent histone gene transcription
Genes Dev. 2000 14: 2283-2297. [Abstract] [Full Text] [PDF]

Tianlin Ma, Brian A. Van Tine, Yue Wei, Michelle D. Garrett, David Nelson, Peter D. Adams, Jin Wang, Jun Qin, Louise T. Chow, and J. Wade Harper: Cell cycle-regulated phosphorylation of p220^NPAT by cyclin E/Cdk2 in Cajal bodies promotes histone gene transcription
Genes Dev. 2000 14: 2298-2313. [Abstract] [Full Text] [PDF]

Robert M. Nissen and Keith R. Yamamoto: The glucocorticoid receptor inhibits NF $kappa$ B by interfering with serine-2 phosphorylation of the RNA polymerase II carboxy-terminal domain
Genes Dev. 2000 14: 2314-2329. [Abstract] [Full Text] [PDF]

Birgit Otzen Petersen, Christian Wagener, Federica Marinoni, Edgar R. Kramer, Marina Melixetian, Eros Lazzerini Denchi, Christian Gieffers, Cristian Matteucci, Jan-Michael Peters, and Kristian Helin: Cell cycle- and cell growth-regulated proteolysis of mammalian CDC6 is dependent on APC-CDH1
Genes Dev. 2000 14: 2330-2343. [Abstract] [Full Text] [PDF]

Atsuya Nishiyama, Kazunori Tachibana, Yuko Igarashi, Hideyo Yasuda, Nobuyuki Tanahashi, Keiji Tanaka, Keita Ohsumi, and Takeo Kishimoto: A nonproteolytic function of the proteasome is required for the dissociation of Cdc2 and cyclin B at the end of M phase
Genes Dev. 2000 14: 2344-2357. [Abstract] [Full Text] [PDF]

Jason D. Weber, John R. Jeffers, Jerold E. Rehg, David H. Randle, Guillermina Lozano, Martine F. Roussel, Charles J. Sherr, and Gerard P. Zambetti: p53-independent functions of the p19^ARF tumor suppressor
Genes Dev. 2000 14: 2358-2365. [Abstract] [Full Text] [PDF]

Horim Lee, Sung-Suk Suh, Eunsook Park, Euna Cho, Ji Hoon Ahn, Sang-Gu Kim, Jong Seob Lee, Young Myung Kwon, and Ilha Lee: The AGAMOUS-LIKE 20 MADS domain protein integrates floral inductive pathways in Arabidopsis
Genes Dev. 2000 14: 2366-2376. [Abstract] [Full Text] [PDF]

Craig D. Fairchild, Michael A. Schumaker, and Peter H. Quail: HFR1 encodes an atypical bHLH protein that acts in phytochrome A signal transduction
Genes Dev. 2000 14: 2377-2391. [Abstract] [Full Text] [PDF]

Cover Caption:

Cover

NPAT activates histone gene transcription. Shown here is an immunofluorescence analysis of NPAT, a substrate of cyclin E-Cdk2,in primary human fibroblast WI38 cells. NPAT is visualized ingreen, and nuclear DNA is stained with DAPI (blue). The cell inS phase (left) is labeled by bromodeoxyuridine (BrdU) incorporation(red). There are four NPAT spots in S-phase cells while thereare only two NPAT spots in G1-phase (BrdU-negative) cells. Allfour NPAT spots in S-phase cells are associated with histone geneclusters on both chromosomes 1 and 6. (For details, see Zhao etal., p. 2283, and Ma et al., p. 2298.)