Genes & Development -- Table of Contents (October 15 2000, 14 [20])

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Volume 14, Issue 20: October 15, 2000 [Index by Author] [Cover Caption]

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Reviews

Research Communications

Research Papers

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Reviews:

Bryan Lemon and Robert Tjian: Orchestrated response: a symphony of transcription factors for gene control
Genes Dev. 2000 14: 2551-2569. [Full Text] [PDF]

Research Communications:

Shuren Liao, Jeanine Graham, and Hong Yan: The function of Xenopus Bloom's syndrome protein homolog (xBLM) in DNA replication
Genes Dev. 2000 14: 2570-2575. [Abstract] [Full Text] [PDF]

Youngsoo Lee, Deborah E. Barnes, Tomas Lindahl, and Peter J. McKinnon: Defective neurogenesis resulting from DNA ligase IV deficiency requires Atm
Genes Dev. 2000 14: 2576-2580. [Abstract] [Full Text] [PDF]

V. Carrie Bromleigh and Leonard P. Freedman: p21 is a transcriptional target of HOXA10 in differentiating myelomonocytic cells
Genes Dev. 2000 14: 2581-2586. [Abstract] [Full Text] [PDF]

Research Papers:

Christopher S. Raymond, Mark W. Murphy, M. Gerard O'Sullivan, Vivian J. Bardwell, and David Zarkower: Dmrt1, a gene related to worm and fly sexual regulators, is required for mammalian testis differentiation
Genes Dev. 2000 14: 2587-2595. [Abstract] [Full Text] [PDF]

Cameron Luitjens, Maria Gallegos, Brian Kraemer, Judith Kimble, and Marvin Wickens: CPEB proteins control two key steps in spermatogenesis in C. elegans
Genes Dev. 2000 14: 2596-2609. [Abstract] [Full Text] [PDF] Supplemental Research Data

Kerstin Lehmann, Elzbieta Janda, Christophe E. Pierreux, Marjatta Rytömaa, Almut Schulze, Martin McMahon, Caroline S. Hill, Hartmut Beug, and Julian Downward: Raf induces TGF $beta$ production while blocking its apoptotic but not invasive responses: a mechanism leading to increased malignancy in epithelial cells
Genes Dev. 2000 14: 2610-2622. [Abstract] [Full Text] [PDF]

Craig D. Kaplan, James R. Morris, C.-ting Wu, and Fred Winston: Spt5 and Spt6 are associated with active transcription and have characteristics of general elongation factors in D. melanogaster
Genes Dev. 2000 14: 2623-2634. [Abstract] [Full Text] [PDF]

Erik D. Andrulis, Ernesto Guzmán, Pascal Döring, Janis Werner, and John T. Lis: High-resolution localization of Drosophila Spt5 and Spt6 at heat shock genes in vivo: roles in promoter proximal pausing and transcription elongation
Genes Dev. 2000 14: 2635-2649. [Abstract] [Full Text] [PDF]

Laura Schramm, P. Shannon Pendergrast, Yuling Sun, and Nouria Hernandez: Different human TFIIIB activities direct RNA polymerase III transcription from TATA-containing and TATA-less promoters
Genes Dev. 2000 14: 2650-2663. [Abstract] [Full Text] [PDF]

Thien-Fah Mah, Konstantin Kuznedelov, Arcady Mushegian, Konstantin Severinov, and Jack Greenblatt: The $alpha$ subunit of E. coli RNA polymerase activates RNA binding by NusA
Genes Dev. 2000 14: 2664-2675. [Abstract] [Full Text] [PDF]

Cover Caption:

Cover

Dmrt1 expression in murine testis. Shown here is a testis section from 14-day-old mouse, stained with an antibody againstthe DM domain protein, Dmrt1. Expression is detected in Sertolicells and spermatogonia. Dmrt1 is a protein related to the sexualregulators Doublesex (DSX) of Drosophila and MAB-3 of C. elegans.Dmrt1 has been implicated in male gonad development in a varietyof vertebrates, based on chromosomal location and expression pattern.Targeted deletion of Dmrt1 in the mouse causes multiple defectsin postnatal testis differentiation. (For details, see Raymondet al., p. 2587.)