Genes & Development -- Table of Contents (November 15 2000, 14 [22])

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Volume 14, Issue 22: November 15, 2000 [Index by Author] [Cover Caption]

Other Issues:

Reviews

Research Communications

Research Papers

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Reviews:

Raphael Kopan and Alison Goate: A common enzyme connects Notch signaling and Alzheimer's disease
Genes Dev. 2000 14: 2799-2806. [Full Text] [PDF]

Research Communications:

Hsin-Ling Hsu, David Gilley, Sanjeev A. Galande, M. Prakash Hande, Beth Allen, Sahn-Ho Kim, Gloria C. Li, Judith Campisi, Terumi Kohwi-Shigematsu, and David J. Chen: Ku acts in a unique way at the mammalian telomere to prevent end joining
Genes Dev. 2000 14: 2807-2812. [Abstract] [Full Text] [PDF]

Alla Y. Karpova, Peter M. Howley, and Lucienne V. Ronco: Dual utilization of an acceptor/donor splice site governs the alternative splicing of the IRF-3 gene
Genes Dev. 2000 14: 2813-2818. [Abstract] [Full Text] [PDF]

Research Papers:

Joyce J. Repa, Guosheng Liang, Jiafu Ou, Yuriy Bashmakov, Jean-Marc A. Lobaccaro, Iichiro Shimomura, Bei Shan, Michael S. Brown, Joseph L. Goldstein, and David J. Mangelsdorf: Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXR $alpha$ and LXR $beta$
Genes Dev. 2000 14: 2819-2830. [Abstract] [Full Text] [PDF]

Joshua R. Schultz, Hua Tu, Alvin Luk, Joyce J. Repa, Julio C. Medina, Leping Li, Susan Schwendner, Shelley Wang, Martin Thoolen, David J. Mangelsdorf, Kevin D. Lustig, and Bei Shan: Role of LXRs in control of lipogenesis
Genes Dev. 2000 14: 2831-2838. [Abstract] [Full Text] [PDF]

Min Liu, Fred A. Pereira, Steven D. Price, Mei-jin Chu, Cindy Shope, Donna Himes, Ruth Anne Eatock, William E. Brownell, Anna Lysakowski, and Ming-Jer Tsai: Essential role of BETA2/NeuroD1 in development of the vestibular and auditory systems
Genes Dev. 2000 14: 2839-2854. [Abstract] [Full Text] [PDF]

Brian K. Kennedy, David A. Barbie, Marie Classon, Nicholas Dyson, and Ed Harlow: Nuclear organization of DNA replication in primary mammalian cells
Genes Dev. 2000 14: 2855-2868. [Abstract] [Full Text] [PDF]

Christopher D. Day, Elsa Lee, Janell Kobayashi, Lynn D. Holappa, Henrik Albert, and David W. Ow: Transgene integration into the same chromosome location can produce alleles that express at a predictable level, or alleles that are differentially silenced
Genes Dev. 2000 14: 2869-2880. [Abstract] [Full Text] [PDF]

Nancy J. Crisona, Terence R. Strick, David Bensimon, Vincent Croquette, and Nicholas R. Cozzarelli: Preferential relaxation of positively supercoiled DNA by E. coli topoisomerase IV in single-molecule and ensemble measurements
Genes Dev. 2000 14: 2881-2892. [Abstract] [Full Text] [PDF]

Gelin Wang, Kazuhito Amanai, Bing Wang, and Jin Jiang: Interactions with Costal2 and Suppressor of fused regulate nuclear translocation and activity of Cubitus interruptus
Genes Dev. 2000 14: 2893-2905. [Abstract] [Full Text] [PDF]

Muriel Boube, Christian Faucher, Laurent Joulia, David L. Cribbs, and Henri-Marc Bourbon: Drosophila homologs of transcriptional mediator complex subunits are required for adult cell and segment identity specification
Genes Dev. 2000 14: 2906-2917. [Abstract] [Full Text] [PDF]

Cover Caption:

Cover

Regulation of subcellular localization and activity of Cubitus interruptus (Ci) by Costal2 and Suppressor of fused. Shownhere is a late third instar wing imaginal disc stained with antibodiesdirected against Ci (red) and the membrane and cytoplasm marker,Armadillo (green). The disc was treated with Leptomycin B beforeimmunostaining to allow for visualization of Ci in the nucleus.Hedgehog induces stabilization and nuclear translocation of full-lengthCi in anterior compartment cells near the anterior-posterior compartmentboundary. (For details, see Wang et al., p. 2893.)