Genes & Development -- Table of Contents (December 15 2000, 14 [24])

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Volume 14, Issue 24: December 15, 2000 [Index by Author] [Cover Caption]

Other Issues:

Reviews

Research Communications

Research Papers

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Reviews:

Serge Nef and Luis F. Parada: Hormones in male sexual development
Genes Dev. 2000 14: 3075-3086. [Full Text] [PDF]

Research Communications:

Encina M. Gonzalez, Kimberly Fekany-Lee, Amanda Carmany-Rampey, Caroline Erter, Jacek Topczewski, Christopher V.E. Wright, and Lilianna Solnica-Krezel: Head and trunk in zebrafish arise via coinhibition of BMP signaling by bozozok and chordino
Genes Dev. 2000 14: 3087-3092. [Abstract] [Full Text] [PDF]

Research Papers:

Claudia Petritsch, Hartmut Beug, Allan Balmain, and Martin Oft: TGF- $beta$ inhibits p70 S6 kinase via protein phosphatase 2A to induce G₁ arrest
Genes Dev. 2000 14: 3093-3101. [Abstract] [Full Text] [PDF]

Jodi R. Alt, John L. Cleveland, Mark Hannink, and J. Alan Diehl: Phosphorylation-dependent regulation of cyclin D1 nuclear export and cyclin D1-dependent cellular transformation
Genes Dev. 2000 14: 3102-3114. [Abstract] [Full Text] [PDF]

Philip D. Jeffrey, Lily Tong, and Nikola P. Pavletich: Structural basis of inhibition of CDK-cyclin complexes by INK4 inhibitors
Genes Dev. 2000 14: 3115-3125. [Abstract] [Full Text] [PDF]

Vitor Barbosa, Rochele R. Yamamoto, Daryl S. Henderson, and David M. Glover: Mutation of a Drosophila gamma tubulin ring complex subunit encoded by discs degenerate-4 differentially disrupts centrosomal protein localization
Genes Dev. 2000 14: 3126-3139. [Abstract] [Full Text] [PDF]

Russell T. Collins and Jessica E. Treisman: Osa-containing Brahma chromatin remodeling complexes are required for the repression of Wingless target genes
Genes Dev. 2000 14: 3140-3152. [Abstract] [Full Text] [PDF]

David H. Lum, Patricia E. Kuwabara, David Zarkower, and Andrew M. Spence: Direct protein-protein interaction between the intracellular domain of TRA-2 and the transcription factor TRA-1A modulates feminizing activity in C. elegans
Genes Dev. 2000 14: 3153-3165. [Abstract] [Full Text] [PDF]

Jun Zhu and Adrian R. Krainer: Pre-mRNA splicing in the absence of an SR protein RS domain
Genes Dev. 2000 14: 3166-3178. [Abstract] [Full Text] [PDF]

Michelle D. Tallquist, Richard A. Klinghoffer, Rainer Heuchel, Peter F. Mueting-Nelsen, Philip D. Corrin, Carl-Henrik Heldin, Richard J. Johnson, and Philippe Soriano: Retention of PDGFR- $beta$ function in mice in the absence of phosphatidylinositol 3'-kinase and phospholipase C $gamma$ signaling pathways
Genes Dev. 2000 14: 3179-3190. [Abstract] [Full Text] [PDF]

David M. Adelman, Marina Gertsenstein, Andras Nagy, M. Celeste Simon, and Emin Maltepe: Placental cell fates are regulated in vivo by HIF-mediated hypoxia responses
Genes Dev. 2000 14: 3191-3203. [Abstract] [Full Text] [PDF]

Jeong Kyo Yoon and Barbara Wold: The bHLH regulator pMesogenin1 is required for maturation and segmentation of paraxial mesoderm
Genes Dev. 2000 14: 3204-3214. [Abstract] [Full Text] [PDF]

Cover Caption:

Cover

Abnormal mitotic spindle formation in Drosophila disc degenerate-4 (dd4) mutant cells. Shown here is the localization of centrosomeassociated protein CP190 with respect to spindle microtubulesin a dd4 mutant cell at anaphase. dd4 encodes a 91 kD subunitof the Drosophila gamma tubulin ring complex. Immunostaining revealsthat antibodies directed against CP190 (red) are weakly associatedwith the spindle poles, and accumulate in the vicinity of themitotic chromosomes. The spindle microtubules are stained withantibodies directed against $alpha$ -tubulin (green). In dd4 mutant cells, $gamma$ -tubulin is dispersed throughout the cell. Thus, intact $gamma$ -tubulinring complex appears to be required at the poles in order to maintainthe polar association of the CP190 protein. (For details, seeBarbosa et al., p. 3126.)