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Volume 14, Issue 3:  February 1, 2000  [Index by Author]  [Cover Caption] 

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Other Issues:
  Reviews
  Research Communications
  Research Papers
  Errata
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Reviews:

Michael M. Neff, Christian Fankhauser, and Joanne Chory
Light: an indicator of time and place
Genes Dev. 2000 14: 257-271. [Full Text] [PDF]  

Research Communications:

Andrew L. Kung, Vivienne I. Rebel, Roderick T. Bronson, Lian-Ee Ch'ng, Colin A. Sieff, David M. Livingston, and Tso-Pang Yao
Gene dose-dependent control of hematopoiesis and hematologic tumor suppression by CBP
Genes Dev. 2000 14: 272-277. [Abstract] [Full Text] [PDF]  

Research Papers:

Nabil H. Chehab, Asra Malikzay, Michael Appel, and Thanos D. Halazonetis
Chk2/hCds1 functions as a DNA damage checkpoint in G1 by stabilizing p53
Genes Dev. 2000 14: 278-288. [Abstract] [Full Text] [PDF]  

Sheau-Yann Shieh, Jinwoo Ahn, Katsuyuki Tamai, Yoichi Taya, and Carol Prives
The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites
Genes Dev. 2000 14: 289-300. [Abstract] [Full Text] [PDF]  

Min Wu, Timothy J. Hemesath, Clifford M. Takemoto, Martin A. Horstmann, Audrey G. Wells, E. Roydon Price, Daniel Z. Fisher, and David E. Fisher
c-Kit triggers dual phosphorylations, which couple activation and degradation of the essential melanocyte factor Mi
Genes Dev. 2000 14: 301-312. [Abstract] [Full Text] [PDF]  

Irina Stancheva and Richard R. Meehan
Transient depletion of xDnmt1 leads to premature gene activation in Xenopus embryos
Genes Dev. 2000 14: 313-327. [Abstract] [Full Text] [PDF]  

Nobushige Nakajo, Satoshi Yoshitome, Jun Iwashita, Maki Iida, Katsuhiro Uto, Shuichi Ueno, Kengo Okamoto, and Noriyuki Sagata
Absence of Wee1 ensures the meiotic cell cycle in Xenopus oocytes
Genes Dev. 2000 14: 328-338. [Abstract] [Full Text] [PDF]  

Qian Tan, K. Liisi Linask, Richard H. Ebright, and Nancy A. Woychik
Activation mutants in yeast RNA polymerase II subunit RPB3 provide evidence for a structurally conserved surface required for activation in eukaryotes and bacteria
Genes Dev. 2000 14: 339-348. [Abstract] [Full Text] [PDF]  

Sofia J. Araújo, Franck Tirode, Frederic Coin, Helmut Pospiech, Juhani E. Syväoja, Manuel Stucki, Ulrich Hübscher, Jean-Marc Egly, and Richard D. Wood
Nucleotide excision repair of DNA with recombinant human proteins: definition of the minimal set of factors, active forms of TFIIH, and modulation by CAK
Genes Dev. 2000 14: 349-359. [Abstract] [Full Text] [PDF]  

Megumi Kasahara, Jennifer A. Clikeman, David B. Bates, and Tokio Kogoma
RecA protein-dependent R-loop formation in vitro
Genes Dev. 2000 14: 360-365. [Abstract] [Full Text] [PDF]  

Dale O. Cowley and Barbara J. Graves
Phosphorylation represses Ets-1 DNA binding by reinforcing autoinhibition
Genes Dev. 2000 14: 366-376. [Abstract] [Full Text] [PDF]  

Véronique Morel and François Schweisguth
Repression by Suppressor of Hairless and activation by Notch are required to define a single row of single-minded expressing cells in the Drosophila embryo
Genes Dev. 2000 14: 377-388. [Abstract] [Full Text] [PDF]  

Errata:


Genes Dev. 2000 14: 389. [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.


Cover Caption:

Cover

CBP has tumor-suppressing activity. Shown here is a histological analysis of a histiocytic sarcoma from a CBP heterozygous mouse. Tumors of hematologic origin developed in CBP+/- animals but not in wild-type littermates or in p300+/- animals. Analysis of the CBP locus revealed a loss of heterozygosity, with specific loss of the wild-type allele and retention of the disrupted allele (not shown). (For details, see Kung et al., p. 272.)



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