Genes & Development -- Table of Contents (February 15 2000, 14 [4])

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Volume 14, Issue 4: February 15, 2000 [Index by Author] [Cover Caption]

Other Issues:

Research Communications

Research Papers

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Research Communications:

Wayne Zundel, Cornelia Schindler, Daphne Haas-Kogan, Albert Koong, Fiona Kaper, Eunice Chen, Alexander R. Gottschalk, Heather E. Ryan, Randall S. Johnson, Anne B. Jefferson, David Stokoe, and Amato J. Giaccia: Loss of PTEN facilitates HIF-1-mediated gene expression
Genes Dev. 2000 14: 391-396. [Abstract] [Full Text] [PDF]

Eric J. Brown and David Baltimore: ATR disruption leads to chromosomal fragmentation and early embryonic lethality
Genes Dev. 2000 14: 397-402. [Abstract] [Full Text] [PDF]

Research Papers:

Stéphan Vagner, Christine Vagner, and Iain W. Mattaj: The carboxyl terminus of vertebrate poly(A) polymerase interacts with U2AF 65 to couple 3'-end processing and splicing
Genes Dev. 2000 14: 403-413. [Abstract] [Full Text] [PDF]

Andrew Yueh and Robert J. Schneider: Translation by ribosome shunting on adenovirus and hsp70 mRNAs facilitated by complementarity to 18S rRNA
Genes Dev. 2000 14: 414-421. [Abstract] [Full Text] [PDF]

Brian C. Freeman, Sara J. Felts, David O. Toft, and Keith R. Yamamoto: The p23 molecular chaperones act at a late step in intracellular receptor action to differentially affect ligand efficacies
Genes Dev. 2000 14: 422-434. [Abstract] [Full Text] [PDF]

Stéphane Germain, Michael Howell, Graeme M. Esslemont, and Caroline S. Hill: Homeodomain and winged-helix transcription factors recruit activated Smads to distinct promoter elements via a common Smad interaction motif
Genes Dev. 2000 14: 435-451. [Abstract] [Full Text] [PDF]

Tzu-Hao Cheng and Marc R. Gartenberg: Yeast heterochromatin is a dynamic structure that requires silencers continuously
Genes Dev. 2000 14: 452-463. [Abstract] [Full Text] [PDF]

Jixuan Li, Gang Ning, and Stephen A. Duncan: Mammalian hepatocyte differentiation requires the transcription factor HNF-4 $alpha$
Genes Dev. 2000 14: 464-474. [Abstract] [Full Text] [PDF]

Florian Frugier, Simone Poirier, Béatrice Satiat-Jeunemaître, Adam Kondorosi, and Martin Crespi: A Krüppel-like zinc finger protein is involved in nitrogen-fixing root nodule organogenesis
Genes Dev. 2000 14: 475-482. [Abstract] [Full Text] [PDF]

Eugene W. Crawford, Jr. and Lawrence J. Shimkets: The stringent response in Myxococcus xanthus is regulated by SocE and the CsgA C-signaling protein
Genes Dev. 2000 14: 483-492. [Abstract] [Full Text] [PDF]

Rita S. Cha, Beth M. Weiner, Scott Keeney, Job Dekker, and N. Kleckner: Progression of meiotic DNA replication is modulated by interchromosomal interaction proteins, negatively by Spo11p and positively by Rec8p
Genes Dev. 2000 14: 493-503. [Abstract] [Full Text] [PDF]

Cover Caption:

Cover

Chromosome fragmentation in ATR^/ cells. Shown here is an analysis of ATR^/ blastocysts cultured in the presence of nocodozole and stainedwith Hoechst to visualize the DNA. Extensive fragmentation ofthe chromosomes is seen. The level of fragmentation was similarto that seen in blastocysts treated with caspase-3 inhibitor (notshown). (For details, see Brown and Baltimore, p. 397.)