Genes & Development -- Table of Contents (April 15 2000, 14 [8])

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Volume 14, Issue 8: April 15, 2000 [Index by Author] [Cover Caption]

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Perspectives

Research Communications

Research Papers

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Perspectives:

Gertraud W. Robinson, Lothar Hennighausen, and Peter F. Johnson: Side-branching in the mammary gland: the progesterone-Wnt connection
Genes Dev. 2000 14: 889-894. [Full Text] [PDF] Supplemental Research Data

Research Communications:

Weiquan Li, Min Han, and Kun-Liang Guan: The leucine-rich repeat protein SUR-8 enhances MAP kinase activation and forms a complex with Ras and Raf
Genes Dev. 2000 14: 895-900. [Abstract] [Full Text] [PDF]

Sharon B. Sokol and Patricia E. Kuwabara: Proteolysis in Caenorhabditis elegans sex determination: cleavage of TRA-2A by TRA-3
Genes Dev. 2000 14: 901-906. [Abstract] [Full Text] [PDF]

Marcus P. Cooper, Amrita Machwe, David K. Orren, Robert M. Brosh, Dale Ramsden, and Vilhelm A. Bohr: Ku complex interacts with and stimulates the Werner protein
Genes Dev. 2000 14: 907-912. [Abstract] [Full Text] [PDF]

Research Papers:

Lisa Homesley, Ming Lei, Yasuo Kawasaki, Sara Sawyer, Tim Christensen, and Bik K. Tye: Mcm10 and the MCM2-7 complex interact to initiate DNA synthesis and to release replication factors from origins
Genes Dev. 2000 14: 913-926. [Abstract] [Full Text] [PDF]

Yi Wang, David Cortez, Parvin Yazdi, Norma Neff, Stephen J. Elledge, and Jun Qin: BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures
Genes Dev. 2000 14: 927-939. [Abstract] [Full Text] [PDF]

Dirk Schübeler, Claire Francastel, Daniel M. Cimbora, Andreas Reik, David I.K. Martin, and Mark Groudine: Nuclear localization and histone acetylation: a pathway for chromatin opening and transcriptional activation of the human $beta$ -globin locus
Genes Dev. 2000 14: 940-950. [Abstract] [Full Text] [PDF]

Oranart Matangkasombut, Robin M. Buratowski, Nathan W. Swilling, and Stephen Buratowski: Bromodomain factor 1 corresponds to a missing piece of yeast TFIID
Genes Dev. 2000 14: 951-962. [Abstract] [Full Text] [PDF]

Alexander Soukas, Paul Cohen, Nicholas D. Socci, and Jeffrey M. Friedman: Leptin-specific patterns of gene expression in white adipose tissue
Genes Dev. 2000 14: 963-980. [Abstract] [Full Text] [PDF]

Renbin Zhao, Kurt Gish, Maureen Murphy, Yuxin Yin, Daniel Notterman, William H. Hoffman, Edward Tom, David H. Mack, and Arnold J. Levine: Analysis of p53-regulated gene expression patterns using oligonucleotide arrays
Genes Dev. 2000 14: 981-993. [Abstract] [Full Text] [PDF]

Silvia Marino, Marc Vooijs, Hanneke van der Gulden, Jos Jonkers, and Anton Berns: Induction of medulloblastomas in p53-null mutant mice by somatic inactivation of Rb in the external granular layer cells of the cerebellum
Genes Dev. 2000 14: 994-1004. [Abstract] [Full Text] [PDF]

Sung Han Park, Su Hyun Park, Hang Gyeong Chin, Moo Je Cho, Robert A. Martienssen, and Chang-deok Han: Inhibitor of striate conditionally suppresses cell proliferation in variegated maize
Genes Dev. 2000 14: 1005-1016. [Abstract] [Full Text] [PDF]

Cover Caption:

Cover

Nuclear compartmentalization as a mediator of chromatin remodeling. Shown here is a fluorescent in situ hybridization analysisof the localization of the human $beta$ -globin locus in interphaseT-MEL (top) or $Delta$ 2-5 MEL (bottom) nuclei. The DNA is shown in blue,the centromeres in red, and the $beta$ -globin locus in green. In the $Delta$ 2-5 MEL hybrid, the $beta$ -globin locus is found away from the centromeres,regardless of the $beta$ -globin transcription. In contrast, the $beta$ -globinlocus is in close proximity to centromeres in T-MEL hybrids harboringa silent, closed locus. (For details, see Schübeler et al., p.940.)