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Volume 15, Issue 17:  September 1, 2001  [Index by Author]  [Cover Caption] 

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Other Issues:
  Reviews
  Research Communications
  Research Papers
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Reviews:

Robert T. Abraham
Cell cycle checkpoint signaling through the ATM and ATR kinases
Genes Dev. 2001 15: 2177-2196. [Full Text] [PDF]  

Research Communications:

Katerina R. Katsani, Juan J. Arredondo, Arnoud J. Kal, and C. Peter Verrijzer
A homeotic mutation in the trithorax SET domain impedes histone binding
Genes Dev. 2001 15: 2197-2202. [Abstract] [Full Text] [PDF]  

William S. Chen, Pei-Zhang Xu, Kathrin Gottlob, Mei-Ling Chen, Karen Sokol, Tanya Shiyanova, Igor Roninson, Wei Weng, Ryo Suzuki, Kazuyuki Tobe, Takashi Kadowaki, and Nissim Hay
Growth retardation and increased apoptosis in mice with homozygous disruption of the akt1 gene
Genes Dev. 2001 15: 2203-2208. [Abstract] [Full Text] [PDF]  

François Spitz, Federico Gonzalez, Catherine Peichel, Thomas F. Vogt, Denis Duboule, and József Zákány
Large scale transgenic and cluster deletion analysis of the HoxD complex separate an ancestral regulatory module from evolutionary innovations
Genes Dev. 2001 15: 2209-2214. [Abstract] [Full Text] [PDF]  

Research Papers:

Akio Yamashita, Tetsuo Ohnishi, Isao Kashima, Yoichi Taya, and Shigeo Ohno
Human SMG-1, a novel phosphatidylinositol 3-kinase-related protein kinase, associates with components of the mRNA surveillance complex and is involved in the regulation of nonsense-mediated mRNA decay
Genes Dev. 2001 15: 2215-2228. [Abstract] [Full Text] [PDF]  

Juraj Gregan, Martin Kolisek, and Rudolf J. Schweyen
Mitochondrial Mg2+ homeostasis is critical for group II intron splicing in vivo
Genes Dev. 2001 15: 2229-2237. [Abstract] [Full Text] [PDF]  

Damien D'Amours and Stephen P. Jackson
The yeast Xrs2 complex functions in S phase checkpoint regulation
Genes Dev. 2001 15: 2238-2249. [Abstract] [Full Text] [PDF] Supplemental Research Data  

George Steele-Perkins, Wei Fang, Xiao-Hong Yang, Mireille Van Gele, Tobias Carling, Jian Gu, Inge M. Buyse, Jonathon A. Fletcher, Jinsong Liu, Roderick Bronson, Robert B. Chadwick, Albert de la Chapelle, Xiao-kun Zhang, Frank Speleman, and Shi Huang
Tumor formation and inactivation of RIZ1, an Rb-binding member of a nuclear protein-methyltransferase superfamily
Genes Dev. 2001 15: 2250-2262. [Abstract] [Full Text] [PDF]  

Jian Hua, Paula Grisafi, Shu-Hua Cheng, and Gerald R. Fink
Plant growth homeostasis is controlled by the Arabidopsis BON1 and BAP1 genes
Genes Dev. 2001 15: 2263-2272. [Abstract] [Full Text] [PDF]  

Sudeshna Kar and Sankar Adhya
Recruitment of HU by piggyback: a special role of GalR in repressosome assembly
Genes Dev. 2001 15: 2273-2281. [Abstract] [Full Text] [PDF]  

Matthew Chaney, Ricardo Grande, Siva R. Wigneshweraraj, Wendy Cannon, Paul Casaz, Maria-Trinidad Gallegos, Jorg Schumacher, Susan Jones, Sarah Elderkin, Angel Ernesto Dago, Enrique Morett, and Martin Buck
Binding of transcriptional activators to sigma 54 in the presence of the transition state analog ADP-aluminum fluoride: insights into activator mechanochemical action
Genes Dev. 2001 15: 2282-2294. [Abstract] [Full Text] [PDF]  

Damien Brégeon, Vincent Colot, Miroslav Radman, and François Taddei
Translational misreading: a tRNA modification counteracts a +2 ribosomal frameshift
Genes Dev. 2001 15: 2295-2306. [Abstract] [Full Text] [PDF]  

Tammy Ellis, Laure Gambardella, Markus Horcher, Stefan Tschanz, Janine Capol, Paula Bertram, Wolfram Jochum, Yann Barrandon, and Meinrad Busslinger
The transcriptional repressor CDP (Cutl1) is essential for epithelial cell differentiation of the lung and the hair follicle
Genes Dev. 2001 15: 2307-2319. [Abstract] [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.


Cover Caption:

Cover

Akt1 is required for cell growth and survival in a mammalian organism. Shown here is a hematoxylin/eosin (H&E) stained section of a seminiferous tubule from a five-week-old Akt1-/- mouse. As visualized by H&E staining, the arrangement of the normal layer of differentiating germ cells is disturbed, the thickness of germ cells in the tubules is uneven, and multinucleated giant cells are present in the lumen. Akt1-/- mice also display increased spontaneous apoptosis in the testes and thymi as compared to wild-type littermates. (For details, see Chen et al., p. 2203.)



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