Genes & Development -- Table of Contents (October 1 2001, 15 [19])

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Volume 15, Issue 19: October 1, 2001 [Index by Author] [Cover Caption]

Other Issues:

Perspectives

Research Communications

Research Papers

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Perspectives:

Richard K. Bruick and Steven L. McKnight: Building better vasculature
Genes Dev. 2001 15: 2497-2502. [Full Text] [PDF]

Stephen T. Smale: Core promoters: active contributors to combinatorial gene regulation
Genes Dev. 2001 15: 2503-2508. [Full Text] [PDF]

Research Communications:

Sylvain Poux, Raffaella Melfi, and Vincenzo Pirrotta: Establishment of Polycomb silencing requires a transient interaction between PC and ESC
Genes Dev. 2001 15: 2509-2514. [Abstract] [Full Text] [PDF]

Jennifer E.F. Butler and James T. Kadonaga: Enhancer-promoter specificity mediated by DPE or TATA core promoter motifs
Genes Dev. 2001 15: 2515-2519. [Abstract] [Full Text] [PDF]

Research Papers:

David A. Elson, Gavin Thurston, L. Eric Huang, David G. Ginzinger, Donald M. McDonald, Randall S. Johnson, and Jeffrey M. Arbeit: Induction of hypervascularity without leakage or inflammation in transgenic mice overexpressing hypoxia-inducible factor-1 $alpha$
Genes Dev. 2001 15: 2520-2532. [Abstract] [Full Text] [PDF]

Ying Qian, Bernd Fritzsch, Senji Shirasawa, Chih-Li Chen, Yoojin Choi, and Qiufu Ma: Formation of brainstem (nor)adrenergic centers and first-order relay visceral sensory neurons is dependent on homeodomain protein Rnx/Tlx3
Genes Dev. 2001 15: 2533-2545. [Abstract] [Full Text] [PDF]

Michael J. Lisbin, Jan Qiu, and Kalpana White: The neuron-specific RNA-binding protein ELAV regulates neuroglian alternative splicing in neurons and binds directly to its pre-mRNA
Genes Dev. 2001 15: 2546-2561. [Abstract] [Full Text] [PDF]

Donald Evans, Ismael Perez, Margaret MacMorris, Devin Leake, Carol J. Wilusz, and Thomas Blumenthal: A complex containing CstF-64 and the SL2 snRNP connects mRNA 3' end formation and trans-splicing in C. elegans operons
Genes Dev. 2001 15: 2562-2571. [Abstract] [Full Text] [PDF]

Hubert Jäger, Alf Herzig, Christian F. Lehner, and Stefan Heidmann: Drosophila Separase is required for sister chromatid separation and binds to PIM and THR
Genes Dev. 2001 15: 2572-2584. [Abstract] [Full Text] [PDF]

James G. Umen and Ursula W. Goodenough: Chloroplast DNA methylation and inheritance in Chlamydomonas
Genes Dev. 2001 15: 2585-2597. [Abstract] [Full Text] [PDF]

Tetsuro Yahata, Wenlin Shao, Hideaki Endoh, Jingyung Hur, Kathryn R. Coser, Huiping Sun, Yoshitaka Ueda, Shigeaki Kato, Kurt J. Isselbacher, Myles Brown, and Toshi Shioda: Selective coactivation of estrogen-dependent transcription by CITED1 CBP/p300-binding protein
Genes Dev. 2001 15: 2598-2612. [Abstract] [Full Text] [PDF]

María L. Ballesteros, Cordelia Bolle, Luisa M. Lois, James M. Moore, Jean-Philippe Vielle-Calzada, Ueli Grossniklaus, and Nam-Hai Chua: LAF1, a MYB transcription activator for phytochrome A signaling
Genes Dev. 2001 15: 2613-2625. [Abstract] [Full Text] [PDF]

Cover Caption:

Cover

Constitutive expression of hypoxia-inducible factor-1 $alpha$ (HIF-1 $alpha$ ) in skin produces a nonleaky hypervascularity. Shown here isan ear skin whole mount from a K14-HIF-1 $alpha$ $Delta$ ODD transgenic mouseexpressing a mutant HIF-1 $alpha$ resistant to proteosomal degradationunder the control of the keratin-14 promoter. The mouse was perfusedwith biotinylated Lysopersicon esculentum lectin to visualizethe microvasculature following peroxidase staining. There is adoubling of vessel density in transgenic compared to nontransgenicskin. Despite a 13-fold induction of VEGF mRNA and a threefoldincrease in VEGF protein, the vasculature is resistant to leakageand the skin is not inflamed (For details, see Elson et al., p.2520.)