Genes & Development -- Table of Contents (December 1 2001, 15 [23])

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Volume 15, Issue 23: December 1, 2001 [Index by Author] [Cover Caption]

Other Issues:

Perspectives

Reviews

Research Papers

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Perspectives:

Peter K. Jackson: A new RING for SUMO: wrestling transcriptional responses into nuclear bodies with PIAS family E3 SUMO ligases
Genes Dev. 2001 15: 3053-3058. [Full Text] [PDF]

Reviews:

Philip W. Ingham and Andrew P. McMahon: Hedgehog signaling in animal development: paradigms and principles
Genes Dev. 2001 15: 3059-3087. [Full Text] [PDF]

Research Papers:

Shrikesh Sachdev, Laurakay Bruhn, Heidemarie Sieber, Andrea Pichler, Frauke Melchior, and Rudolf Grosschedl: PIASy, a nuclear matrix-associated SUMO E3 ligase, represses LEF1 activity by sequestration into nuclear bodies
Genes Dev. 2001 15: 3088-3103. [Abstract] [Full Text] [PDF]

Emmanuelle Querido, Paola Blanchette, Qin Yan, Takumi Kamura, Megan Morrison, Dominique Boivin, William G. Kaelin, Ronald C. Conaway, Joan Weliky Conaway, and Philip E. Branton: Degradation of p53 by adenovirus E4orf6 and E1B55K proteins occurs via a novel mechanism involving a Cullin-containing complex
Genes Dev. 2001 15: 3104-3117. [Abstract] [Full Text] [PDF]

Sue Biggins and Andrew W. Murray: The budding yeast protein kinase Ipl1/Aurora allows the absence of tension to activate the spindle checkpoint
Genes Dev. 2001 15: 3118-3129. [Abstract] [Full Text] [PDF]

Scott L. Page and R. Scott Hawley: c(3)G encodes a Drosophila synaptonemal complex protein
Genes Dev. 2001 15: 3130-3143. [Abstract] [Full Text] [PDF]

LeAnn Howe, Darryl Auston, Patrick Grant, Sam John, Richard G. Cook, Jerry L. Workman, and Lorraine Pillus: Histone H3 specific acetyltransferases are essential for cell cycle progression
Genes Dev. 2001 15: 3144-3154. [Abstract] [Full Text] [PDF]

Shigehiro Osada, Ann Sutton, Nemone Muster, Christine E. Brown, John R. Yates, III, Rolf Sternglanz, and Jerry L. Workman: The yeast SAS (something about silencing) protein complex contains a MYST-type putative acetyltransferase and functions with chromatin assembly factor ASF1
Genes Dev. 2001 15: 3155-3168. [Abstract] [Full Text] [PDF]

Sebastiaan H. Meijsing and Ann E. Ehrenhofer-Murray: The silencing complex SAS-I links histone acetylation to the assembly of repressed chromatin by CAF-I and Asf1 in Saccharomyces cerevisiae
Genes Dev. 2001 15: 3169-3182. [Abstract] [Full Text] [PDF]

Jianqiang Huang, Chih-Jian Lih, Kuang-Hung Pan, and Stanley N. Cohen: Global analysis of growth phase responsive gene expression and regulation of antibiotic biosynthetic pathways in Streptomyces coelicolor using DNA microarrays
Genes Dev. 2001 15: 3183-3192. [Abstract] [Full Text] [PDF]

Jeremy S. Dasen, Juan-Pedro Martinez Barbera, Thomas S. Herman, Shawn O' Connell, Lorin Olson, BongGun Ju, Jessica Tollkuhn, Sung Hee Baek, David W. Rose, and Michael G. Rosenfeld: Temporal regulation of a paired-like homeodomain repressor/TLE corepressor complex and a related activator is required for pituitary organogenesis
Genes Dev. 2001 15: 3193-3207. [Abstract] [Full Text] [PDF]

Thomas Åskov Pedersen, Elisabeth Kowenz-Leutz, Achim Leutz, and Claus Nerlov: Cooperation between C/EBP $alpha$ TBP/TFIIB and SWI/SNF recruiting domains is required for adipocyte differentiation
Genes Dev. 2001 15: 3208-3216. [Abstract] [Full Text] [PDF]

Zhaoxia Sun and Nancy Hopkins: vhnf1, the MODY5 and familial GCKD-associated gene, regulates regional specification of the zebrafish gut, pronephros, and hindbrain
Genes Dev. 2001 15: 3217-3229. [Abstract] [Full Text] [PDF]

Cover Caption:

Cover

Subnuclear sequestration of LEF1 by protein inhibitor of activated STAT-y (PIASy). Shown here are immunofluorescence analysesof COS7 cells that were transfected with expression constructsencoding LEF1 or T7-PIASy. LEF1 is distributed throughout thenucleus (green, upper left panel). PIASy, a nuclear matrix-associatedSUMO E3 ligase, is localized in punctate subnuclear structures(red, lower left panel). Coexpression of LEF1 with PIASy resultsin a striking redistribution of LEF1 (green, center panel) intopunctate structures that colocalize with PIASy (red, center panel).PIASy- and LEF1-containing nuclear bodies do not colocalize withheterochromatin (red, upper right panel), but partially colocalizewith a subset of PML nuclear bodies (red, lower right panel),(For details, see Sachdev et al., p. 3088.)