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Volume 15, Issue 24:  December 15, 2001  [Index by Author]  [Cover Caption] 

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Other Issues:
  Perspectives
  Research Communications
  Research Papers
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Perspectives:

Richard R. Meehan, Sari Pennings, and Irina Stancheva
Lashings of DNA methylation, forkfuls of chromatin remodeling
Genes Dev. 2001 15: 3231-3236. [Full Text] [PDF]  

Research Communications:

Andrew J. Pierce, Peng Hu, Mingguang Han, Nathan Ellis, and Maria Jasin
Ku DNA end-binding protein modulates homologous repair of double-strand breaks in mammalian cells
Genes Dev. 2001 15: 3237-3242. [Abstract] [Full Text] [PDF]  

Erica L. Jackson, Nicholas Willis, Kim Mercer, Roderick T. Bronson, Denise Crowley, Raymond Montoya, Tyler Jacks, and David A. Tuveson
Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras
Genes Dev. 2001 15: 3243-3248. [Abstract] [Full Text] [PDF]  

Research Papers:

Galen H. Fisher, Shari L. Wellen, David Klimstra, Joi M. Lenczowski, Jay W. Tichelaar, Martin J. Lizak, Jeffrey A. Whitsett, Alan Koretsky, and Harold E. Varmus
Induction and apoptotic regression of lung adenocarcinomas by regulation of a K-Ras transgene in the presence and absence of tumor suppressor genes
Genes Dev. 2001 15: 3249-3262. [Abstract] [Full Text] [PDF]  

Nguan Soon Tan, Liliane Michalik, Noa Noy, Rubina Yasmin, Corinne Pacot, Manuel Heim, Beat Flühmann, Beatrice Desvergne, and Walter Wahli
Critical roles of PPARbeta /delta in keratinocyte response to inflammation
Genes Dev. 2001 15: 3263-3277. [Abstract] [Full Text] [PDF]  

Julie D.R. Reimann, Bryan E. Gardner, Florence Margottin-Goguet, and Peter K. Jackson
Emi1 regulates the anaphase-promoting complex by a different mechanism than Mad2 proteins
Genes Dev. 2001 15: 3278-3285. [Abstract] [Full Text] [PDF]  

Scott D. Briggs, Mary Bryk, Brian D. Strahl, Wang L. Cheung, Judith K. Davie, Sharon Y.R. Dent, Fred Winston, and C. David Allis
Histone H3 lysine 4 methylation is mediated by Set1 and required for cell growth and rDNA silencing in Saccharomyces cerevisiae
Genes Dev. 2001 15: 3286-3295. [Abstract] [Full Text] [PDF]  

Jean-Yves Masson, Madalena C. Tarsounas, Alicja Z. Stasiak, Andrzej Stasiak, Rajvee Shah, Michael J. McIlwraith, Fiona E. Benson, and Stephen C. West
Identification and purification of two distinct complexes containing the five RAD51 paralogs
Genes Dev. 2001 15: 3296-3307. [Abstract] [Full Text] [PDF]  

Stefan Sigurdsson, Stephen Van Komen, Wendy Bussen, David Schild, Joanna S. Albala, and Patrick Sung
Mediator function of the human Rad51B-Rad51C complex in Rad51/RPA-catalyzed DNA strand exchange
Genes Dev. 2001 15: 3308-3318. [Abstract] [Full Text] [PDF]  

Eun-Jung Cho, Michael S. Kobor, Minkyu Kim, Jack Greenblatt, and Stephen Buratowski
Opposing effects of Ctk1 kinase and Fcp1 phosphatase at Ser 2 of the RNA polymerase II C-terminal domain
Genes Dev. 2001 15: 3319-3329. [Abstract] [Full Text] [PDF]  

Maxim V. Sukhodolets, Julio E. Cabrera, Huijun Zhi, and Ding Jun Jin
RapA, a bacterial homolog of SWI2/SNF2, stimulates RNA polymerase recycling in transcription
Genes Dev. 2001 15: 3330-3341. [Abstract] [Full Text] [PDF]  

Antonin V. Tutter, Christy J. Fryer, and Katherine A. Jones
Chromatin-specific regulation of LEF-1-beta -catenin transcription activation and inhibition in vitro
Genes Dev. 2001 15: 3342-3354. [Abstract] [Full Text] [PDF]  

Noritaka Matsumoto and Kiyotaka Okada
A homeobox gene, PRESSED FLOWER, regulates lateral axis-dependent development of Arabidopsis flowers
Genes Dev. 2001 15: 3355-3364. [Abstract] [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.


Cover Caption:

Cover

A conditional murine model of pulmonary adenocarcinoma reveals a role for K-Ras in lung tumorigenesis in the presence and absence of tumor suppressor genes. Shown here in the background is a TUNEL staining demonstrating apoptotic tumor cells following de-induction of mutant K-Ras in a tetracycline-regulated model of K-Ras-driven lung adenocarcinoma. Inset is a transverse MRI image demonstrating diffuse lung tumors in the same mouse. (For details, see Fisher et al., p. 3249; also see related paper by Jackson et al., p. 3243.)



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