Genes & Development -- Table of Contents (February 15 2001, 15 [4])

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Volume 15, Issue 4: February 15, 2001 [Index by Author] [Cover Caption]

Other Issues:

Reviews

Research Communications

Research Papers

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Reviews:

Marie-Pierre Gulli and Matthias Peter: Temporal and spatial regulation of Rho-type guanine-nucleotide exchange factors: the yeast perspective
Genes Dev. 2001 15: 365-379. [Full Text] [PDF]

Research Communications:

Stéphane Ansieau, Lothar J. Strobl, and Achim Leutz: Activation of the Notch-regulated transcription factor CBF1/RBP-J $kappa$ through the 13SE1A oncoprotein
Genes Dev. 2001 15: 380-385. [Abstract] [Full Text] [PDF]

Ulrike Ziebold, Tammi Reza, Alicia Caron, and Jacqueline A. Lees: E2F3 contributes both to the inappropriate proliferation and to the apoptosis arising in Rb mutant embryos
Genes Dev. 2001 15: 386-391. [Abstract] [Full Text] [PDF]

John F. Ross, Anders Näär, Hieu Cam, Richard Gregory, and Brian David Dynlacht: Active repression and E2F inhibition by pRB are biochemically distinguishable
Genes Dev. 2001 15: 392-397. [Abstract] [Full Text] [PDF]

Ruben D. Ramirez, Carmela P. Morales, Brittney-Shea Herbert, Jeffrey M. Rohde, Christina Passons, Jerry W. Shay, and Woodring E. Wright: Putative telomere-independent mechanisms of replicative aging reflect inadequate growth conditions
Genes Dev. 2001 15: 398-403. [Abstract] [Full Text] [PDF]

Research Papers:

Abha Chandra, Timothy R. Hughes, Constance I. Nugent, and Victoria Lundblad: Cdc13 both positively and negatively regulates telomere replication
Genes Dev. 2001 15: 404-414. [Abstract] [Full Text] [PDF]

Oleg N. Voloshin, Benjamin E. Ramirez, Ad Bax, and R. Daniel Camerini-Otero: A model for the abrogation of the SOS response by an SOS protein: a negatively charged helix in DinI mimics DNA in its interaction with RecA
Genes Dev. 2001 15: 415-427. [Abstract] [Full Text] [PDF]

David C. Schultz, Josh R. Friedman, and Frank J. Rauscher, III: Targeting histone deacetylase complexes via KRAB-zinc finger proteins: the PHD and bromodomains of KAP-1 form a cooperative unit that recruits a novel isoform of the Mi-2 $alpha$ subunit of NuRD
Genes Dev. 2001 15: 428-443. [Abstract] [Full Text] [PDF]

Anne Grapin-Botton, Amit R. Majithia, and Douglas A. Melton: Key events of pancreas formation are triggered in gut endoderm by ectopic expression of pancreatic regulatory genes
Genes Dev. 2001 15: 444-454. [Abstract] [Full Text] [PDF]

Dug Keun Lee, Seok Hee Park, Youngsuk Yi, Shin-Geon Choi, Cecile Lee, W. Tony Parks, HyeSeong Cho, Mark P. de Caestecker, Yosef Shaul, Anita B. Roberts, and Seong-Jin Kim: The hepatitis B virus encoded oncoprotein pX amplifies TGF- $beta$ family signaling through direct interaction with Smad4: potential mechanism of hepatitis B virus-induced liver fibrosis
Genes Dev. 2001 15: 455-466. [Abstract] [Full Text] [PDF]

Shu Takeda, Jean-Pierre Bonnamy, Michael J. Owen, Patricia Ducy, and Gerard Karsenty: Continuous expression of Cbfa1 in nonhypertrophic chondrocytes uncovers its ability to induce hypertrophic chondrocyte differentiation and partially rescues Cbfa1-deficient mice
Genes Dev. 2001 15: 467-481. [Abstract] [Full Text] [PDF]

Cover Caption:

Cover

Cbfa1 is a hypertrophic chondrocyte differentiation factor. Shown here is an in situ hybridization analysis of Cbfa1 expressionin a scapula section of a 14.5 dpc mouse embryo. As visualizedby the Cbfa1 probe (red), Cbfa1 is expressed in prehypertrophicchondrocytes and to a lesser extent in hypertrophic chondrocytes.Cbfa1 expression precedes and is required for hypertrophic chondrocytedifferentiation in some skeletal elements. (For details, see Takedaet al., p. 467.)