Genes & Development -- Table of Contents (September 1 2002, 16 [17])

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Volume 16, Issue 17: September 1, 2002 [Index by Author] [Cover Caption]

Other Issues:

Perspectives

Reviews

Research Communications

Research Papers

Errata

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Perspectives:

Martijn de Jager and Roland Kanaar: Genome instability and Rad50^S: subtle yet severe
Genes Dev. 2002 16: 2173-2178. [Full Text] [PDF]

Reviews:

J. Wade Harper, Janet L. Burton, and Mark J. Solomon: The anaphase-promoting complex: it's not just for mitosis any more
Genes Dev. 2002 16: 2179-2206. [Full Text] [PDF]

Research Communications:

Kenneth J. Ritchie, Michael P. Malakhov, Christopher J. Hetherington, Liming Zhou, Marie-Terese Little, Oxana A. Malakhova, Jack C. Sipe, Stuart H. Orkin, and Dong-Er Zhang: Dysregulation of protein modification by ISG15 results in brain cell injury
Genes Dev. 2002 16: 2207-2212. [Abstract] [Full Text] [PDF]

Jeroen Stuurman, Fabienne Jäggi, and Cris Kuhlemeier: Shoot meristem maintenance is controlled by a GRAS-gene mediated signal from differentiating cells
Genes Dev. 2002 16: 2213-2218. [Abstract] [Full Text] [PDF]

Simona Saccani and Gioacchino Natoli: Dynamic changes in histone H3 Lys 9 methylation occurring at tightly regulated inducible inflammatory genes
Genes Dev. 2002 16: 2219-2224. [Abstract] [Full Text] [PDF]

Judd C. Rice, Kenichi Nishioka, Kavitha Sarma, Ruth Steward, Danny Reinberg, and C. David Allis: Mitotic-specific methylation of histone H4 Lys 20 follows increased PR-Set7 expression and its localization to mitotic chromosomes
Genes Dev. 2002 16: 2225-2230. [Abstract] [Full Text] [PDF] Supplemental Research Data

Joseph A. Martens and Fred Winston: Evidence that Swi/Snf directly represses transcription in S. cerevisiae
Genes Dev. 2002 16: 2231-2236. [Abstract] [Full Text] [PDF]

Research Papers:

Carla F. Bender, Michael L. Sikes, Ruth Sullivan, Leslie Erskine Huye, Michelle M. Le Beau, David B. Roth, Olga K. Mirzoeva, Eugene M. Oltz, and John H. J. Petrini: Cancer predisposition and hematopoietic failure in Rad50^S/S mice
Genes Dev. 2002 16: 2237-2251. [Abstract] [Full Text] [PDF]

Claudio Talora, Dennis C. Sgroi, Christopher P. Crum, and G. Paolo Dotto: Specific down-modulation of Notch1 signaling in cervical cancer cells is required for sustained HPV-E6/E7 expression and late steps of malignant transformation
Genes Dev. 2002 16: 2252-2263. [Abstract] [Full Text] [PDF]

Anja Sterner-Kock, Irmgard S. Thorey, Katri Koli, Frank Wempe, Jürgen Otte, Thorsten Bangsow, Katharina Kuhlmeier, Thomas Kirchner, Shenchu Jin, Jorma Keski-Oja, and Harald von Melchner: Disruption of the gene encoding the latent transforming growth factor- $beta$ binding protein 4 (LTBP-4) causes abnormal lung development, cardiomyopathy, and colorectal cancer
Genes Dev. 2002 16: 2264-2273. [Abstract] [Full Text] [PDF]

Laurie E. Littlepage and Joan V. Ruderman: Identification of a new APC/C recognition domain, the A box, which is required for the Cdh1-dependent destruction of the kinase Aurora-A during mitotic exit
Genes Dev. 2002 16: 2274-2285. [Abstract] [Full Text] [PDF] Supplemental Research Data

David A. Prober and Bruce A. Edgar: Interactions between Ras1, dMyc, and dPI3K signaling in the developing Drosophila wing
Genes Dev. 2002 16: 2286-2299. [Abstract] [Full Text] [PDF] Supplemental Research Data

Christina Waldsich, Rupert Grossberger, and Renée Schroeder: RNA chaperone StpA loosens interactions of the tertiary structure in the td group I intron in vivo
Genes Dev. 2002 16: 2300-2312. [Abstract] [Full Text] [PDF]

Errata:

: Errata for vol. 16, p. 1616
Genes Dev. 2002 16: 2313. [Full Text] [PDF]

Cover Caption:

Cover

Expression of an activated form of Drosophila Ras induces phosphoinositide 3-kinase (dPI3K) signaling in the developing wing.Shown here is an immunofluorescence analysis of a Drosophila imaginalwing disc using antibodies directed against the cell membranemarker CD2 (red). Clones of cells overexpressing dPI3K lack CD2(red), and are enlarged due to increased rates of cellular growth.The levels and localization of phosphatidylinositol-3,4,5-triphosphate(PIP3), a second messenger generated by dPI3K, are visualizedby a constitutively expressed reporter construct containing apleckstrin homology domain fused to green fluorescent protein(GPH, green). GPH accumulates in the nucleus and cytoplasm ofwild-type cells, but is recruited to the cell membrane of cellsoverexpressing dPI3K. (For details, see Prober and Edgar, p. 2286.)