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Volume 16, Issue 18:  September 15, 2002  [Index by Author]  [Cover Caption] 

Cover Image
Other Issues:
  Perspectives
  Research Communications
  Research Papers
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Perspectives:

Jin Jiang
Degrading Ci: who is Cul-pable?
Genes Dev. 2002 16: 2315-2321. [Full Text] [PDF]  

Jonathan Hodgkin
The remarkable ubiquity of DM domain factors as regulators of sexual phenotype: ancestry or aptitude?
Genes Dev. 2002 16: 2322-2326. [Full Text] [PDF]  

Research Communications:

Patrick J. Lupardus, Tony Byun, Muh-ching Yee, Mohammad Hekmat-Nejad, and Karlene A. Cimprich
A requirement for replication in activation of the ATR-dependent DNA damage checkpoint
Genes Dev. 2002 16: 2327-2332. [Abstract] [Full Text] [PDF]  

Doug W. Chan, Benjamin Ping-Chi Chen, Sheela Prithivirajsingh, Akihiro Kurimasa, Michael D. Story, Jun Qin, and David J. Chen
Autophosphorylation of the DNA-dependent protein kinase catalytic subunit is required for rejoining of DNA double-strand breaks
Genes Dev. 2002 16: 2333-2338. [Abstract] [Full Text] [PDF]  

Jane Brennan, Dominic P. Norris, and Elizabeth J. Robertson
Nodal activity in the node governs left-right asymmetry
Genes Dev. 2002 16: 2339-2344. [Abstract] [Full Text] [PDF]  

Xiaodong Wang and Helen M. Chamberlin
Multiple regulatory changes contribute to the evolution of the Caenorhabditis lin-48 ovo gene
Genes Dev. 2002 16: 2345-2349. [Abstract] [Full Text] [PDF]  

Research Papers:

Annie Andrieux, Paul A. Salin, Muriel Vernet, Pekka Kujala, Julie Baratier, Sylvie Gory-Fauré, Christophe Bosc, Hervé Pointu, Dominique Proietto, Annie Schweitzer, Eric Denarier, Judith Klumperman, and Didier Job
The suppression of brain cold-stable microtubules in mice induces synaptic defects associated with neuroleptic-sensitive behavioral disorders
Genes Dev. 2002 16: 2350-2364. [Abstract] [Full Text] [PDF]  

Martin M. Riccomagno, Lenka Martinu, Michael Mulheisen, Doris K. Wu, and Douglas J. Epstein
Specification of the mammalian cochlea is dependent on Sonic hedgehog
Genes Dev. 2002 16: 2365-2378. [Abstract] [Full Text] [PDF]  

Melissa A. Henriksen, Aurel Betz, Marc V. Fuccillo, and James E. Darnell, Jr.
Negative regulation of STAT92E by an N-terminally truncated STAT protein derived from an alternative promoter site
Genes Dev. 2002 16: 2379-2389. [Abstract] [Full Text] [PDF] Supplemental Research Data  

Robyn Lints and Scott W. Emmons
Regulation of sex-specific differentiation and mating behavior in C. elegans by a new member of the DM domain transcription factor family
Genes Dev. 2002 16: 2390-2402. [Abstract] [Full Text] [PDF]  

Chan-Yen Ou, Yi-Fan Lin, Ying-Jiun Chen, and Cheng-Ting Chien
Distinct protein degradation mechanisms mediated by Cul1 and Cul3 controlling Ci stability in Drosophila eye development
Genes Dev. 2002 16: 2403-2414. [Abstract] [Full Text] [PDF]  

Jose Bessa, Brian Gebelein, Franck Pichaud, Fernando Casares, and Richard S. Mann
Combinatorial control of Drosophila eye development by Eyeless, Homothorax, and Teashirt
Genes Dev. 2002 16: 2415-2427. [Abstract] [Full Text] [PDF]  

Amy J. MacQueen, Mónica P. Colaiácovo, Kent McDonald, and Anne M. Villeneuve
Synapsis-dependent and -independent mechanisms stabilize homolog pairing during meiotic prophase in C. elegans
Genes Dev. 2002 16: 2428-2442. [Abstract] [Full Text] [PDF]  

Alf Herzig, Christian F. Lehner, and Stefan Heidmann
Proteolytic cleavage of the THR subunit during anaphase limits Drosophila separase function
Genes Dev. 2002 16: 2443-2454. [Abstract] [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.


Cover Caption:

Cover

The C. elegans DM domain gene mab-23 defines the pattern of dopaminergic fate expression among sex-specific sensory neurons in the male nervous system. Shown here is the ventral view of a C. elegans male expressing a gfp reporter transgene for the dopaminergic cell fate marker cat-2 (tyrosine hydroxylase) in male-specific ray sensory neurons. The C. elegans male tail is sexually specialized and bears nine bilateral pairs of finger-like ray sensory organs, embedded in an acellular fan. The rays are used to sense the hermaphrodite during mating. mab-23 activity confines CAT-2::GFP expression to three pairs of ray neurons. The CAT-2::GFP chimeric protein also localizes to sensory dendritic endings for unknown reasons. (For details, see Lints and Emmons, p. 2390.)



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