Genes & Development -- Table of Contents (February 15 2002, 16 [4])

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Volume 16, Issue 4: February 15, 2002 [Index by Author] [Cover Caption]

Other Issues:

Reviews

Research Communications

Research Papers

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Reviews:

Tatsuya Hirano: The ABCs of SMC proteins: two-armed ATPases for chromosome condensation, cohesion, and repair
Genes Dev. 2002 16: 399-414. [Full Text] [PDF]

Research Communications:

Cary K. Lai, Michael C. Miller, and Kathleen Collins: Template boundary definition in Tetrahymena telomerase
Genes Dev. 2002 16: 415-420. [Abstract] [Full Text] [PDF]

Pascal te Welscher, Marian Fernandez-Teran, Marian A. Ros, and Rolf Zeller: Mutual genetic antagonism involving GLI3 and dHAND prepatterns the vertebrate limb bud mesenchyme prior to SHH signaling
Genes Dev. 2002 16: 421-426. [Abstract] [Full Text] [PDF]

Research Papers:

François Roy, Gino Laberge, Mélanie Douziech, David Ferland-McCollough, and Marc Therrien: KSR is a scaffold required for activation of the ERK/MAPK module
Genes Dev. 2002 16: 427-438. [Abstract] [Full Text] [PDF]

Matti Davis, Ada Hatzubai, Jens S. Andersen, Etti Ben-Shushan, Gregory Zvi Fisher, Avraham Yaron, Asne Bauskin, Frank Mercurio, Matthias Mann, and Yinon Ben-Neriah: Pseudosubstrate regulation of the SCF^-TrCP ubiquitin ligase by hnRNP-U
Genes Dev. 2002 16: 439-451. [Abstract] [Full Text] [PDF]

Kyungho Lee, Witoon Tirasophon, Xiaohua Shen, Marek Michalak, Ron Prywes, Tetsuya Okada, Hiderou Yoshida, Kazutoshi Mori, and Randal J. Kaufman: IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response
Genes Dev. 2002 16: 452-466. [Abstract] [Full Text] [PDF]

Yi Wei Jiang: Transcriptional cosuppression of yeast Ty1 retrotransposons
Genes Dev. 2002 16: 467-478. [Abstract] [Full Text] [PDF]

Kenichi Nishioka, Sergei Chuikov, Kavitha Sarma, Hediye Erdjument-Bromage, C. David Allis, Paul Tempst, and Danny Reinberg: Set9, a novel histone H3 methyltransferase that facilitates transcription by precluding histone tail modifications required for heterochromatin formation
Genes Dev. 2002 16: 479-489. [Abstract] [Full Text] [PDF]

Peter Brodersen, Morten Petersen, Helen M. Pike, Brian Olszak, Søren Skov, Niels Ødum, Lise Bolt Jørgensen, Rhoderick E. Brown, and John Mundy: Knockout of Arabidopsis ACCELERATED-CELL-DEATH11 encoding a sphingosine transfer protein causes activation of programmed cell death and defense
Genes Dev. 2002 16: 490-502. [Abstract] [Full Text] [PDF]

David S. Fay, Sean Keenan, and Min Han: fzr-1 and lin-35/Rb function redundantly to control cell proliferation in C. elegans as revealed by a nonbiased synthetic screen
Genes Dev. 2002 16: 503-517. [Abstract] [Full Text] [PDF]

Thomas Kusch, Tobias Storck, Uwe Walldorf, and Rolf Reuter: Brachyury proteins regulate target genes through modular binding sites in a cooperative fashion
Genes Dev. 2002 16: 518-529. [Abstract] [Full Text] [PDF]

Cover Caption:

Cover

C. elegans fzr-1 synthetically interacts with lin-35/Rb to regulate global cell proliferation. Shown here in the foregroundare schematic worm colonies representing a lin-35 synthetic-lethalscreen analogous to an S. cerevisiae sectoring assay. The GFP⁺ animals (green) carry an extrachromosomal array containing wildtype rescuing copies of lin-35 and a GFP reporter; the GFP animals (pale yellow) have lost this array. The worm colony shownin the lower left failed to segregate wild type-appearing (large)GFP animals, indicating the presence of a mutation that makes survivaldependent upon the lin-35-expressing array. Shown in the backgroundare GFP⁺ and GFP animals from a lin-35; fzr-1 double-mutant strain identifiedby such a screen. The GFP animals are small and display a hyperproliferation and sterilephenotype. (For details, see Fay et al., p. 503.)