Genes & Development -- Table of Contents (May 15 2003, 17 [10])

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Volume 17, Issue 10: May 15, 2003 [Index by Author] [Cover Caption]

Other Issues:

Reviews

Research Communications

Research Papers

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Reviews:

Laura Alonso and Elaine Fuchs: Stem cells in the skin: waste not, Wnt not
Genes Dev. 2003 17: 1189-1200. [Full Text] [PDF]

Research Communications:

Yutaka Yoshida, Takahisa Nakamura, Masato Komoda, Hitoshi Satoh, Toru Suzuki, Junko K. Tsuzuku, Takashi Miyasaka, Eri H. Yoshida, Hisashi Umemori, Reiko K. Kunisaki, Kenzaburo Tani, Shunsuke Ishii, Shigeo Mori, Masami Suganuma, Tetsuo Noda, and Tadashi Yamamoto: Mice lacking a transcriptional corepressor Tob are predisposed to cancer
Genes Dev. 2003 17: 1201-1206. [Abstract] [Full Text] [PDF] Supplemental Research Data

Luke T. Krebs, Naomi Iwai, Shigenori Nonaka, Ian C. Welsh, Yu Lan, Rulang Jiang, Yukio Saijoh, Timothy P. O'Brien, Hiroshi Hamada, and Thomas Gridley: Notch signaling regulates left-right asymmetry determination by inducing Nodal expression
Genes Dev. 2003 17: 1207-1212. Published in Advance May 2, 2003, 10.1101/gad.1084703 [Abstract] [Full Text] [PDF] Supplemental Research Data

Ángel Raya, Yasuhiko Kawakami, Concepción Rodríguez-Esteban, Dirk Büscher, Christopher M. Koth, Tohru Itoh, Masanobu Morita, R. Marina Raya, Ilir Dubova, Joaquín Grego Bessa, José Luis de la Pompa, and Juan Carlos Izpisúa Belmonte: Notch activity induces Nodal expression and mediates the establishment of left-right asymmetry in vertebrate embryos
Genes Dev. 2003 17: 1213-1218. Published in Advance May 2, 2003, 10.1101/gad.1084403 [Abstract] [Full Text] [PDF]

David Van Mater, Frank T. Kolligs, Andrzej A. Dlugosz, and Eric R. Fearon: Transient activation of $beta$ -catenin signaling in cutaneous keratinocytes is sufficient to trigger the active growth phase of the hair cycle in mice
Genes Dev. 2003 17: 1219-1224. [Abstract] [Full Text] [PDF]

Research Papers:

Dayalan G. Srinivasan, Ridgely M. Fisk, Huihong Xu, and Sander van den Heuvel: A complex of LIN-5 and GPR proteins regulates G protein signaling and spindle function in C. elegans
Genes Dev. 2003 17: 1225-1239. Published in Advance May 2, 2003, 10.1101/gad.1081203 [Abstract] [Full Text] [PDF] Supplemental Research Data

Alan Jian Zhu, Limin Zheng, Kaye Suyama, and Matthew P. Scott: Altered localization of Drosophila Smoothened protein activates Hedgehog signal transduction
Genes Dev. 2003 17: 1240-1252. Published in Advance May 2, 2003, 10.1101/gad.1080803 [Abstract] [Full Text] [PDF] Supplemental Research Data

Gabriela Dontu, Wissam M. Abdallah, Jessica M. Foley, Kyle W. Jackson, Michael F. Clarke, Mari J. Kawamura, and Max S. Wicha: In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells
Genes Dev. 2003 17: 1253-1270. [Abstract] [Full Text] [PDF] Supplemental Research Data

Claire R. Weston, Anthony Wong, J. Perry Hall, Mary E.P. Goad, Richard A. Flavell, and Roger J. Davis: JNK initiates a cytokine cascade that causes Pax2 expression and closure of the optic fissure
Genes Dev. 2003 17: 1271-1280. [Abstract] [Full Text] [PDF]

Thomas J. Santangelo, Rachel Anne Mooney, Robert Landick, and Jeffrey W. Roberts: RNA polymerase mutations that impair conversion to a termination-resistant complex by Q antiterminator proteins
Genes Dev. 2003 17: 1281-1292. [Abstract] [Full Text] [PDF]

Wilma Ross, David A. Schneider, Brian J. Paul, Aaron Mertens, and Richard L. Gourse: An intersubunit contact stimulating transcription initiation by E. coli RNA polymerase: interaction of the $alpha$ C-terminal domain and $sigma$ region 4
Genes Dev. 2003 17: 1293-1307. [Abstract] [Full Text] [PDF]

Cover Caption:

Cover

Drosophila salivary gland cells, which are several hundred times bigger than embryonic and imaginal disc cells, are capableof responding to Hedgehog signaling. Shown here are early thirdinstar larval salivary gland cells taken from transgenic fliesproducing GFP-tagged Smoothened (GFP-Smo) and Hedgehog (Hh). Withoutadded Hh, low amounts of GFP-Smo are located in a network of intracellularstructures (not shown). In salivary gland cells where an activeform of Hh signal (HhN) is produced, GFP-Smo (green) undergoesa dramatic translocation to the cell surface. 7AAD (red) is usedas a nuclear marker. (For details, see Zhu et al., p. 1240.)