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Cover The type I MADS-box gene PHERES1 is a primary target of the Polycomb group protein MEDEA in Arabidopsis. Shown here is a wild-type, heart-stage Arabidopsis seed expressing a PHERES1::
-GLUCURONIDASE transgene. After fertilization, PHERES1 is transiently expressed in the embryo and the endosperm. When seeds reach the heart stage, PHERES1 expression becomes restricted to the chalazal region of the endosperm (shown here). In medea mutant seeds, PHERES1 is highly expressed until the seeds abort. (For details, see Kohler et al., p. 1540.)