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Cover The chaplins, a novel family of hydrophobic cell-surface proteins (ChpA-H), are essential for the formation of aerial hyphae in the filamentous bacterium Streptomyces coelicolor. Shown here is aerial hyphae formation in an S. coelicolor strain in which five chaplin genes were deleted (chpABCDH). The chpABCDH strain only formed a few aerial hyphae on solid medium even after 8 d of growth. (For details, see Claessen et al., p. 1714, and related paper by Elliot et al., p. 1727.)

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