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Volume 17, Issue 19:  October 1, 2003  [Index by Author]  [Cover Caption] 

Cover Image
Other Issues:
  Perspectives
  Research Communications
  Research Papers
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Perspectives:

Alison A. Bertuch and Victoria Lundblad
Which end: dissecting Ku's function at telomeres and double-strand breaks
Genes Dev. 2003 17: 2347-2350. [Full Text] [PDF]  

Agamemnon J. Carpousis
Degradation of targeted mRNAs in Escherichia coli: regulation by a small antisense RNA
Genes Dev. 2003 17: 2351-2355. [Full Text] [PDF]  

Research Communications:

Judith A. Sharp, Denise C. Krawitz, Kelly A. Gardner, Catherine A. Fox, and Paul D. Kaufman
The budding yeast silencing protein Sir1 is a functional component of centromeric chromatin
Genes Dev. 2003 17: 2356-2361. Published in Advance September 15, 2003, 10.1101/gad.1131103 [Abstract] [Full Text] [PDF] Supplemental Research Data  

Kai Jiao, Holger Kulessa, Kevin Tompkins, Yingna Zhou, Lorene Batts, H. Scott Baldwin, and Brigid L.M. Hogan
An essential role of Bmp4 in the atrioventricular septation of the mouse heart
Genes Dev. 2003 17: 2362-2367. Published in Advance September 15, 2003, 10.1101/gad.1124803 [Abstract] [Full Text] [PDF]  

Raquel Sitcheran, Patricia C. Cogswell, and Albert S. Baldwin, Jr.
NF-{kappa}B mediates inhibition of mesenchymal cell differentiation through a posttranscriptional gene silencing mechanism
Genes Dev. 2003 17: 2368-2373. [Abstract] [Full Text] [PDF]  

Research Papers:

Eric Massé, Freddy E. Escorcia, and Susan Gottesman
Coupled degradation of a small regulatory RNA and its mRNA targets in Escherichia coli
Genes Dev. 2003 17: 2374-2383. Published in Advance September 15, 2003, 10.1101/gad.1127103 [Abstract] [Full Text] [PDF]  

Anne E. Stellwagen, Zara W. Haimberger, Joshua R. Veatch, and Daniel E. Gottschling
Ku interacts with telomerase RNA to promote telomere addition at native and broken chromosome ends
Genes Dev. 2003 17: 2384-2395. Published in Advance September 15, 2003, 10.1101/gad.1125903 [Abstract] [Full Text] [PDF]  

Gregory David, Garth M. Turner, Yao Yao, Alexei Protopopov, and Ronald A. DePinho
mSin3-associated protein, mSds3, is essential for pericentric heterochromatin formation and chromosome segregation in mammalian cells
Genes Dev. 2003 17: 2396-2405. [Abstract] [Full Text] [PDF] Supplemental Research Data  

Frédéric Bantignies, Charlotte Grimaud, Sergey Lavrov, Mathieu Gabut, and Giacomo Cavalli
Inheritance of Polycomb-dependent chromosomal interactions in Drosophila
Genes Dev. 2003 17: 2406-2420. [Abstract] [Full Text] [PDF] Supplemental Research Data  

Arshad Desai, Sonja Rybina, Thomas Müller-Reichert, Andrej Shevchenko, Anna Shevchenko, Anthony Hyman, and Karen Oegema
KNL-1 directs assembly of the microtubule-binding interface of the kinetochore in C. elegans
Genes Dev. 2003 17: 2421-2435. [Abstract] [Full Text] [PDF] Supplemental Research DataSupplemental Research Data - 2  

Tetsuya Amano, Satoshi Yamasaki, Naoko Yagishita, Kaneyuki Tsuchimochi, Hiroshi Shin, Ko-ichi Kawahara, Satoko Aratani, Hidetoshi Fujita, Lei Zhang, Rie Ikeda, Ryoji Fujii, Naoki Miura, Setsuro Komiya, Kusuki Nishioka, Ikuro Maruyama, Akiyoshi Fukamizu, and Toshihiro Nakajima
Synoviolin/Hrd1, an E3 ubiquitin ligase, as a novel pathogenic factor for arthropathy
Genes Dev. 2003 17: 2436-2449. Published in Advance September 15, 2003, 10.1101/gad.1096603 [Abstract] [Full Text] [PDF]  

Mark H.G. Verheijen, Roman Chrast, Patrick Burrola, and Greg Lemke
Local regulation of fat metabolism in peripheral nerves
Genes Dev. 2003 17: 2450-2464. [Abstract] [Full Text] [PDF] Supplemental Research Data  

Attila Aszodi, Ernst B. Hunziker, Cord Brakebusch, and Reinhard Fässler
{beta}1 integrins regulate chondrocyte rotation, G1 progression, and cytokinesis
Genes Dev. 2003 17: 2465-2479. [Abstract] [Full Text] [PDF] Supplemental Research Data  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.


Cover Caption:

Cover Cover The kinetochore forms a dynamic interface with spindle microtubules to segregate chromosomes during mitosis. Shown here are immunofluorescence images of the first mitotic division of the C. elegans embryo, in which the kinetochores have been highlighted using antibodies to the newly identified kinetochore protein KNL-1 (green). Spindle microtubules are labeled in red, and chromosomal DNA in blue. KNL-1 localizes to kinetochores throughout mitosis and is required to translate the initiation of kinetochore assembly into the formation of a functional microtubule-binding interface. (For details, see Desai et al., p. 2421.)


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