Perspectives:

Donald W. Nelson and Richard W. Padgett

Insulin worms its way into the spotlight
Genes Dev. 2003 17: 813-818. [Full Text] [PDF]  

Reviews:

Kim Newton and Andreas Strasser

Caspases signal not only apoptosis but also antigen-induced activation in cells of the immune system
Genes Dev. 2003 17: 819-825. [Full Text] [PDF]  

Research Communications:

Qing-xin Hua, Satoe H. Nakagawa, Jill Wilken, Rowena R. Ramos, Wenhua Jia, Joseph Bass, and Michael A. Weiss

A divergent INS protein in Caenorhabditis elegans structurally resembles human insulin and activates the human insulin receptor
Genes Dev. 2003 17: 826-831. Published in Advance March 21, 2003, 10.1101/gad.1058003 [Abstract] [Full Text] [PDF]  

Ming Jiang and Jo Milner

Bcl-2 constitutively suppresses p53-dependent apoptosis in colorectal cancer cells
Genes Dev. 2003 17: 832-837. [Abstract] [Full Text] [PDF]  

Jude Canon and Utpal Banerjee

In vivo analysis of a developmental circuit for direct transcriptional activation and repression in the same cell by a Runx protein
Genes Dev. 2003 17: 838-843. [Abstract] [Full Text] [PDF]  

Research Papers:

Weiqing Li, Scott G. Kennedy, and Gary Ruvkun

daf-28 encodes a C. elegans insulin superfamily member that is regulated by environmental cues and acts in the DAF-2 signaling pathway
Genes Dev. 2003 17: 844-858. Published in Advance March 21, 2003, 10.1101/gad.1066503 [Abstract] [Full Text] [PDF]  

Vera A. Cherkasova and Alan G. Hinnebusch

Translational control by TOR and TAP42 through dephosphorylation of eIF2 kinase GCN2
Genes Dev. 2003 17: 859-872. Published in Advance March 21, 2003, 10.1101/gad.1069003 [Abstract] [Full Text] [PDF]  

Gang Min Hur, Joseph Lewis, Qingfeng Yang, Yong Lin, Hiroyasu Nakano, Sergei Nedospasov, and Zheng-gang Liu

The death domain kinase RIP has an essential role in DNA damage-induced NF-B activation
Genes Dev. 2003 17: 873-882. Published in Advance March 21, 2003, 10.1101/gad.1062403 [Abstract] [Full Text] [PDF]  

Leonardo Salmena, Benedicte Lemmers, Anne Hakem, Elzbieta Matysiak-Zablocki, Kiichi Murakami, P.Y. Billie Au, Donna M. Berry, Laura Tamblyn, Amro Shehabeldin, Eva Migon, Andrew Wakeham, Denis Bouchard, Wen Chen Yeh, Jane C. McGlade, Pamela S. Ohashi, and Razqallah Hakem

Essential role for caspase 8 in T-cell homeostasis and T-cell-mediated immunity
Genes Dev. 2003 17: 883-895. Published in Advance March 21, 2003, 10.1101/gad.1063703 [Abstract] [Full Text] [PDF]  

Joanna Wysocka, Michael P. Myers, Carol D. Laherty, Robert N. Eisenman, and Winship Herr

Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell-proliferation factor HCF-1
Genes Dev. 2003 17: 896-911. [Abstract] [Full Text] [PDF]  

Katrin Serth, Karin Schuster-Gossler, Ralf Cordes, and Achim Gossler

Transcriptional oscillation of Lunatic fringe is essential for somitogenesis
Genes Dev. 2003 17: 912-925. [Abstract] [Full Text] [PDF]  

Takao Sakai, Shaohua Li, Denitsa Docheva, Carsten Grashoff, Keiko Sakai, Günter Kostka, Attila Braun, Alexander Pfeifer, Peter D. Yurchenco, and Reinhard Fässler

Integrin-linked kinase (ILK) is required for polarizing the epiblast, cell adhesion, and controlling actin accumulation
Genes Dev. 2003 17: 926-940. [Abstract] [Full Text] [PDF]  

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