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Volume 18, Issue 8:  April 15, 2004  [Index by Author]  [Cover Caption] 

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Other Issues:
  Perspectives
  Research Communications
  Research Papers
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Perspectives:

Catherine Denicourt and Steven F. Dowdy
Cip/Kip proteins: more than just CDKs inhibitors
Genes Dev. 2004 18: 851-855. [Full Text] [PDF]  

Research Communications:

Andrew Wilkins, Qinggong Ping, and Christopher L. Carpenter
RhoBTB2 is a substrate of the mammalian Cul3 ubiquitin ligase complex
Genes Dev. 2004 18: 856-861. [Abstract] [Full Text] [PDF]  

Research Papers:

Arnaud Besson, Mark Gurian-West, Anja Schmidt, Alan Hall, and James M. Roberts
p27Kip1 modulates cell migration through the regulation of RhoA activation
Genes Dev. 2004 18: 862-876. Published in Advance April 12, 2004, 10.1101/gad.1185504 [Abstract] [Full Text] [PDF] Supplemental Research Data  

Hitoshi Aihara, Takeya Nakagawa, Kiyoshi Yasui, Tsutomu Ohta, Susumu Hirose, Naoshi Dhomae, Koji Takio, Mayumi Kaneko, Yukio Takeshima, Masami Muramatsu, and Takashi Ito
Nucleosomal histone kinase-1 phosphorylates H2A Thr 119 during mitosis in the early Drosophila embryo
Genes Dev. 2004 18: 877-888. Published in Advance April 12, 2004, 10.1101/gad.1184604 [Abstract] [Full Text] [PDF] Supplemental Research Data  

Yumi Watanabe, Sei Kameoka, Vidya Gopalakrishnan, Kenneth D. Aldape, Zhizhong Z. Pan, Frederick F. Lang, and Sadhan Majumder
Conversion of myoblasts to physiologically active neuronal phenotype
Genes Dev. 2004 18: 889-900. Published in Advance April 12, 2004, 10.1101/gad.1179004 [Abstract] [Full Text] [PDF] Supplemental Research Data  

Andreas Fischer, Nina Schumacher, Manfred Maier, Michael Sendtner, and Manfred Gessler
The Notch target genes Hey1 and Hey2 are required for embryonic vascular development
Genes Dev. 2004 18: 901-911. [Abstract] [Full Text] [PDF] Supplemental Research Data  

Guo-Li Wang, Polina Iakova, Margie Wilde, Samir Awad, and Nikolai A. Timchenko
Liver tumors escape negative control of proliferation via PI3K/Akt-mediated block of C/EBP{alpha} growth inhibitory activity
Genes Dev. 2004 18: 912-925. [Abstract] [Full Text] [PDF]  

Kazuyuki Doi, Takeshi Izawa, Takuichi Fuse, Utako Yamanouchi, Takahiko Kubo, Zenpei Shimatani, Masahiro Yano, and Atsushi Yoshimura
Ehd1, a B-type response regulator in rice, confers short-day promotion of flowering and controls FT-like gene expression independently of Hd1
Genes Dev. 2004 18: 926-936. Published in Advance April 12, 2004, 10.1101/gad.1189604 [Abstract] [Full Text] [PDF] Supplemental Research Data  

Juhee Jeong, Junhao Mao, Toyoaki Tenzen, Andreas H. Kottmann, and Andrew P. McMahon
Hedgehog signaling in the neural crest cells regulates the patterning and growth of facial primordia
Genes Dev. 2004 18: 937-951. [Abstract] [Full Text] [PDF] Supplemental Research Data  

Carolina A. Yoshida, Hiromitsu Yamamoto, Takashi Fujita, Tatsuya Furuichi, Kosei Ito, Ken-ichi Inoue, Kei Yamana, Akira Zanma, Kenji Takada, Yoshiaki Ito, and Toshihisa Komori
Runx2 and Runx3 are essential for chondrocyte maturation, and Runx2 regulates limb growth through induction of Indian hedgehog
Genes Dev. 2004 18: 952-963. [Abstract] [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.


Cover Caption:

Cover Cover The cyclin-dependent kinase inhibitor p27Kip1 regulates cell migration by inhibiting Rho activation. Shown here are p27-null mouse embryo fibroblasts stained with phalloidin (red) to visualize F-actin, vinculin (green) to visualize focal adhesions, and Hoescht 33342 (blue) to visualize DNA. The cells display an increased number of actin stress fibers and focal adhesions, suggesting an enhanced activation of Rho signaling. (For details, see Besson et al., p.862.)


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